⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL28211135 | 0.97 | — | — | |
| Sulfuric Acid SCHEMBL28101971 | 0.84 | TP53 (0.39) | — | |
| SCHEMBL7483246 | 0.75 | — | — | |
| SCHEMBL28129676 | 0.75 | — | — | |
| SCHEMBL6721815 | 0.75 | — | — | |
| SCHEMBL28220452 | 0.75 | — | — | |
| SCHEMBL11076912 | 0.75 | ALDH1A1 (0.36) | — | |
| SCHEMBL7111206 | 0.73 | — | — | |
| SCHEMBL23482666 | 0.71 | — | — | |
| SCHEMBL16409823 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324257-B2 | Mitotic kinesin inhibitors and methods of use thereof | ARRAY BIOPHARMA INC. (US) | 2012-12-04 | — | — | US | claimed |
| US-20100041719-A1 | MITOTIC KINESIN INHIBITORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2010-02-18 | — | — | US | claimed |
| US-20220194907-A1 | PROCESS FOR THE PREPARATION OF MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-06-23 | — | — | US | disclosed |
| CN-111356679-A | Microbicidal oxadiazole derivatives | 先正达参股股份有限公司 | 2020-06-30 | — | — | CN | disclosed |
| CN-105188679-B | The method and system of status adjustment for Fine crystals material | 珍珠治疗公司 | 2018-10-16 | — | — | CN | disclosed |
| WO-2018184987-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-10-11 | — | — | WO | disclosed |
| WO-2018184988-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-10-11 | — | — | WO | disclosed |
| WO-2018184984-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-10-11 | — | — | WO | disclosed |
| CN-108513574-A | N-sulfonylated pyrazolo [3,4-b ] pyridine-6-carboxamides and methods of use | 艾伯维公司 | 2018-09-07 | — | — | CN | disclosed |
| CN-108431002-A | Substituted pyrazolo [3, 4-b ] pyridine-6-carboxylic acids and uses thereof | 艾伯维公司 | 2018-08-21 | — | — | CN | disclosed |
| CN-107304169-A | The method that water-soluble nitrogen-containing compound or its aqueous solution react production product with cyclic ethers | 佳化化学股份有限公司 | 2017-10-31 | — | — | CN | disclosed |
| CN-1604818-A | Catalysts for producing carboxylic acid salts | BASF AG (DE) | 2005-04-06 | — | — | CN | disclosed |
| EP-1448198-A1 | NICOTIN-OR ISONICOTIN BENZOTHIAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-08-25 | — | — | EP | disclosed |
| US-6620811-B2 | Adenosine receptor antagonists; nervous system and cardiovascular disorders; Parkinson*s, Huntington*s, and Alzheimer* disease; antiasthmatics, antiallergens | HOFFMANN-LA ROCHE INC. | 2003-09-16 | — | — | US | disclosed |
| US-20030134854-A1 | Isonicotin- and nicotinamide derivatives of benzothiazoles | F.HOFFMANN-LA ROCHE AG (CH) | 2003-07-17 | — | — | US | disclosed |
| WO-2003043636-A1 | NICOTIN-OR ISONICOTIN BENZOTHIAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-30 | — | — | WO | disclosed |
| EP-0818512-B1 | Quinoline derivative and use of same | MITSUI CHEMICALS INC (JP) | 2002-10-02 | — | — | EP | disclosed |
| US-6407242-B1 | REACTING A PHTHALIMIDE COMPOUND WITH A QUINOLINE COMPOUND;ELECTROLUMINESCENCE | MITSUI CHEMICALS, INC. (JP) | 2002-06-18 | — | — | US | disclosed |
| US-6132640-A | ZINC COMPLEXES OF QUINOLINE | MITSUI CHEMICALS, INC. (JP) | 2000-10-17 | — | — | US | disclosed |
| EP-0818512-A1 | Quinoline derivative and use of same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1998-01-14 | — | — | EP | disclosed |