SCHEMBL4369568

SCHEMBL4369568

NC(=O)NC(=O)OCc1ccco1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.58
TDP1 Q9NUW8 4/20 0.47
MAPK1 P28482 2/20 0.47
MAPT P10636 2/20 0.46
LMNA P02545 2/20 0.46
TP53 P04637 1/20 0.46
HTT P42858 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
SLC1A3 P43003 1/20 0.46
SLC1A2 P43004 1/20 0.46
SLC1A1 P43005 1/20 0.46
MGLL Q99685 1/20 0.45
ALOX5 P09917 1/20 0.45
POLB P06746 4/20 0.45
TSHR P16473 2/20 0.45
HSD17B10 Q99714 1/20 0.43
GAA P10253 2/20 0.41
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11813088 0.88 ALDH1A1 (0.55) ALDH1A1TDP1MAPK1MAPTLMNA
SCHEMBL113906 0.81 ALDH1A1 (0.68) ALDH1A1TDP1MAPK1MAPTLMNA
SCHEMBL14587498 0.80 ALDH1A1 (0.67) ALDH1A1TDP1MAPK1MAPTLMNA
Hydrochloric Acid SCHEMBL4750147 0.80 ALDH1A1 (0.66) ALDH1A1TDP1MAPK1MAPTLMNA
SCHEMBL6443447 0.79 ALDH1A1 (0.70) ALDH1A1TDP1MAPK1MAPTLMNA
SCHEMBL1487382 0.78 ALDH1A1 (0.54) ALDH1A1TDP1MAPK1MAPTTP53
SCHEMBL11002726 0.78 ALDH1A1 (0.68) ALDH1A1TDP1MAPK1MAPTLMNA
SCHEMBL14991432 0.77 ALDH1A1 (0.72) ALDH1A1TDP1MAPK1MAPTLMNA
Cyclohexane SCHEMBL9403768 0.77 ALDH1A1 (0.62) ALDH1A1TDP1MAPK1MAPTLMNA
SCHEMBL10815725 0.76 ALDH1A1 (0.57) ALDH1A1TDP1MAPK1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117654511-A Catalyst and method for preparing 2, 5-tetrahydrofuran dimethanol in water phase by using same 中科国生(杭州)科技有限公司 2024-03-08 CN claimed
US-20180319078-A1 MATERIALS FOR 3D MULTI-STAGE METHOD VOXELJET AG (DE) 2018-11-08 US claimed
EP-0035292-B1 AN ENCLOSURE MEMBER SUBSTANTIALLY IMPERMEABLE TO THE TRANSMISSION OF SOLVENTS AND FUELS KONINKLIJKE EMBALLAGE INDUSTRIE VAN LEER B.V. (NL) 1985-05-22 EP claimed
EP-0015267-B1 MODIFIED FURFURYL ALCOHOL FOUNDRY RESINS ASHLAND OIL, INC. (US) 1984-06-13 EP claimed
US-4371574-A A SULFONATED, NON-AROMATIC POLYMER COATED WITH A MELAMINE-FORMALDEHYDE OR UREA-FORMALDEHYDE CONDENSATION PRODUCT KONINKLIJKE EMBALLAGE INDUSTRIE VAN LEER B.V. (NL) 1983-02-01 US claimed
EP-0035292-A2 An enclosure member substantially impermeable to the transmission of solvents and fuels KONINKLIJKE EMBALLAGE INDUSTRIE VAN LEER B.V. (NL) 1981-09-09 EP claimed
US-4107283-A ION EXCHANGE CORES WITH POLYMERIC COATING, MEDICAL DIAGNOSIS NEW ENGLAND NUCLEAR CORPORATION (US) 1978-08-15 US claimed
US-3993117-A Method for increasing the mechanical resistance of foundry moulds or cores made from a self-hardening liquid sand and a resin as binding agent CENTRE TECHNIQUE DES INDUSTRIES DE LA FONDERIE (FR) 1976-11-23 US claimed
CN-117654511-A Catalyst and method for preparing 2, 5-tetrahydrofuran dimethanol in water phase by using same 中科国生(杭州)科技有限公司 2024-03-08 CN disclosed
CN-212532264-U Tinning equipment for furan resin production 沧州强龙生物科技有限公司 2021-02-12 CN disclosed
CN-106470780-B Method for the layer-by-layer construction of a body comprising a refractory moulding base material and a resol ASK化学品股份有限公司 2019-12-10 CN disclosed
EP-3548200-A1 AMINO ACID-CONTAINING MOULDING MATERIAL MIXTURE FOR PRODUCTION OF MOULDINGS FOR THE FOUNDRY INDUSTRY HÜTTENES-ALBERTUS Chemische Werke Gesellschaft mit beschränkter Haftung (DE) 2019-10-09 EP disclosed
US-10144053-B2 Method for the layer-wise building of bodies comprising refractory mold base material and resoles, and molds or cores manufactured according to said method ASK CHEMICALS GMBH (DE) 2018-12-04 US disclosed
US-20180319078-A1 MATERIALS FOR 3D MULTI-STAGE METHOD VOXELJET AG (DE) 2018-11-08 US disclosed
US-4176114-A Process for manufacturing sand cores or molds C L INDUSTRIES, INC. (US) 1979-11-27 US disclosed
WO-1979000775-A1 MODIFIED UREA FORMALDEHYDE FURFURYL ALCOHOL FOUNDRY RESINS ASHLAND OIL INC (US) 1979-10-18 WO disclosed
US-4107283-A ION EXCHANGE CORES WITH POLYMERIC COATING, MEDICAL DIAGNOSIS NEW ENGLAND NUCLEAR CORPORATION (US) 1978-08-15 US disclosed
US-4033925-A Monomeric furfuryl alcohol-resorcinol foundry binders THE QUAKER OATS COMPANY (US) 1977-07-05 US disclosed
US-3993117-A Method for increasing the mechanical resistance of foundry moulds or cores made from a self-hardening liquid sand and a resin as binding agent CENTRE TECHNIQUE DES INDUSTRIES DE LA FONDERIE (FR) 1976-11-23 US disclosed
US-3993117-A Method for increasing the mechanical resistance of foundry moulds or cores made from a self-hardening liquid sand and a resin as binding agent CENTRE TECHNIQUE DES INDUSTRIES DE LA FONDERIE (FR) 1976-11-23 US disclosed