SCHEMBL15980586

SCHEMBL15980586

CC(=O)Oc1c(Cc2cc(C)cc(C(C)(C)C)c2OC(C)=O)cc(C)cc1C(C)(C)C

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.53
CYP2C9 P11712 2/20 0.51
CYP2C19 P33261 2/20 0.51
HIF1A Q16665 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
CYP2D6 P10635 1/20 0.46
HSD17B10 Q99714 1/20 0.46
ALDH1A1 P00352 1/20 0.40
CA2 P00918 1/20 0.40
POLB P06746 1/20 0.40
TYR P14679 1/20 0.40
LMNA P02545 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4369586 0.93 HSPA5 (0.67) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL8407409 0.86 ALDH1A1 (0.48) HSPA5SMN1; SMN2ALDH1A1CA2POLB
SCHEMBL17546544 0.83 HSPA5 (0.49) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL17546520 0.82 HSPA5 (0.47) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL7194890 0.82 HSPA5 (0.47) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL29407804 0.80 HSPA5 (0.60) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL499728 0.80 HSPA5 (0.60) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL28395857 0.79 HSPA5 (0.63) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL27785927 0.78 HSPA5 (0.46) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL97424 0.78 HSPA5 (0.61) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9341882-B2 Laminate, polarizing plate, liquid crystal display device, and method of manufacturing polarizing plate FUJIFILM CORPORATION (JP) 2016-05-17 US disclosed
US-9341882-B2 Laminate, polarizing plate, liquid crystal display device, and method of manufacturing polarizing plate FUJIFILM CORPORATION (JP) 2016-05-17 US disclosed
US-20140242302-A1 LAMINATE, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE, AND METHOD OF MANUFACTURING POLARIZING PLATE FUJIFILM CORPORATION (JP) 2014-08-28 US disclosed
US-20140242302-A1 LAMINATE, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE, AND METHOD OF MANUFACTURING POLARIZING PLATE FUJIFILM CORPORATION (JP) 2014-08-28 US disclosed