Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiobenzoic Acid SCHEMBL29087097 | 0.95 | SMN1; SMN2 (0.45) | SMN1; SMN2POLBNPSR1LMNANR1I2 | |
| SCHEMBL9333329 | 0.81 | MEN1 (0.53) | SMN1; SMN2POLBNPSR1LMNANR1I2 | |
| SCHEMBL28583395 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2POLBNPSR1LMNANR1I2 | |
| Benzophenone SCHEMBL9307364 | 0.77 | ALDH1A1 (0.54) | SMN1; SMN2POLBNPSR1LMNANR1I2 | |
| SCHEMBL11561182 | 0.76 | KMT2A (0.57) | SMN1; SMN2POLBNPSR1LMNANR1I2 | |
| SCHEMBL11561181 | 0.76 | KMT2A (0.57) | SMN1; SMN2POLBNPSR1LMNANR1I2 | |
| SCHEMBL28654793 | 0.74 | SRC (0.45) | SMN1; SMN2POLBLMNAALDH1A1MEN1 | |
| SCHEMBL28831737 | 0.73 | MEN1 (0.49) | SMN1; SMN2POLBNPSR1LMNANR1I2 | |
| SCHEMBL7719434 | 0.72 | POLB (0.49) | SMN1; SMN2POLBNPSR1LMNANR1I2 | |
| SCHEMBL28531861 | 0.72 | TSHR (0.46) | POLBNPSR1LMNANR1I2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601849-B1 | Nonlinear optical compounds and related macrostructures | UNIVERSITY OF WASHINGTON (US) | 2009-10-13 | — | — | US | disclosed |