Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 19/20 | 1.00 |
| ▸ | HTR6 | P50406 | 2/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5032275 | 0.88 | HRH4 (0.78) | HRH4HTR6HRH3 | |
| SCHEMBL12257800 | 0.86 | HRH4 (0.74) | HRH4 | |
| SCHEMBL22924654 | 0.86 | HRH4 (0.74) | HRH4 | |
| SCHEMBL17309194 | 0.79 | HRH4 (0.66) | HRH4 | |
| SCHEMBL17581165 | 0.79 | HRH4 (0.66) | HRH4HTR6HRH3 | |
| SCHEMBL1966112 | 0.78 | HRH4 (0.64) | HRH4HRH3 | |
| SCHEMBL19439697 | 0.78 | HRH4 (0.64) | HRH4HTR6HRH3 | |
| SCHEMBL12455903 | 0.77 | HRH4 (1.00) | HRH4HTR6 | |
| SCHEMBL27457638 | 0.77 | HRH4 (0.62) | HRH4 | |
| SCHEMBL128037 | 0.76 | HRH4 (0.59) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192626-A1 | NOVEL SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHOD OF USE THEREOF | BAYLOR COLLEGE OF MEDICINE (US) | 2023-06-22 | — | — | US | disclosed |
| EP-2097378-A1 | NOVEL SEH INHIBITORS AND THEIR USE | Smithkline Beecham Corporation (US) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008105968-A1 | NOVEL SEH INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2008-09-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192626-A1 | NOVEL SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHOD OF USE THEREOF | EPHX1, EPHX2, NCEH1 | HRH4 291/4885HTR6 2810/4885HRH3 198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.