Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15671736 | 0.85 | HRH4 (0.44) | HRH4 | |
| SCHEMBL5032275 | 0.85 | HRH4 (0.78) | HRH4HRH3 | |
| SCHEMBL2453047 | 0.84 | ALDH1A1 (0.46) | HRH4 | |
| SCHEMBL15671734 | 0.79 | PKM (0.55) | HRH4 | |
| SCHEMBL4369596 | 0.78 | HRH4 (1.00) | HRH4HRH3 | |
| SCHEMBL17581165 | 0.76 | HRH4 (0.66) | HRH4HRH3 | |
| SCHEMBL19439697 | 0.75 | HRH4 (0.64) | HRH4HRH3 | |
| SCHEMBL3132475 | 0.75 | HRH4 (0.48) | HRH4 | |
| SCHEMBL12455903 | 0.74 | HRH4 (1.00) | HRH4 | |
| SCHEMBL11150401 | 0.73 | HRH4 (0.59) | HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334665-A1 | MODULATORS FOR AMYLOID BETA | F. Hoffmann-La Roche AG (CH) | 2011-06-22 | — | — | EP | disclosed |