SCHEMBL4369740

SCHEMBL4369740

C=CC(=O)N1CCCNCC1C

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.35
JAK3 P52333 3/20 0.33
MAPK1 P28482 1/20 0.33
BTK Q06187 1/20 0.32
ENPP2 Q13822 1/20 0.31
DPP4 P27487 1/20 0.31
SLC6A1 P30531 2/20 0.31
SLC6A11 P48066 1/20 0.31
TSHR P16473 1/20 0.31
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
SLC6A13 Q9NSD5 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30
ATM Q13315 1/20 0.30
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4364897 0.90 DPP4 (0.37) SRCJAK3BTKENPP2DPP4
SCHEMBL16117959 0.90 DPP4 (0.37) SRCJAK3BTKENPP2DPP4
SCHEMBL23595333 0.90 DPP4 (0.37) SRCJAK3BTKENPP2DPP4
SCHEMBL20161862 0.80 SRC (0.33) SRCMAPK1
SCHEMBL25259854 0.79 SLC6A1 (0.38) DPP4SLC6A1SLC6A11TSHRLMNA
SCHEMBL11893793 0.79 SLC6A1 (0.38) DPP4SLC6A1SLC6A11TSHRLMNA
SCHEMBL15322517 0.79 SRC (0.34) SRCMAPK1SLC6A1SLC6A11TSHR
SCHEMBL20892969 0.77 SRC (0.45) SRCJAK3MAPK1BTKDPP4
SCHEMBL11931515 0.77 SRC (0.45) SRCJAK3MAPK1BTKDPP4
SCHEMBL32667654 0.77 SRC (0.45) SRCJAK3MAPK1BTKDPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090291310-A1 OPAL LATEX SUN CHEMICAL CORPORATION 2009-11-26 US disclosed
US-7365120-B2 Polymer composite, stretched product thereof and production processes therefor KAWAMURA INSTITUTE OF CHEMICAL RESEARCH (JP) 2008-04-29 US disclosed
US-20080058499-A1 Three-dimensional periodic structure, three-dimensional periodic porous structure, and method for producing these KAWAMURA INSTITUTE OF CHEMICAL RESEARCH (JP) 2008-03-06 US disclosed
EP-1589038-B1 Polymer composite, stretched product thereof and production processes therefor KAWAMURA INST CHEM RES (JP) 2007-01-24 EP disclosed
US-20060078736-A1 Three-dimensional periodic structure, three-dimensional periodic porous structure, and method for producing these KAWAMURA INSTITUTE OF CHEMICAL RESEARCH (JP) 2006-04-13 US disclosed
EP-1589038-A1 Polymer composite, stretched product thereof and production processes therefor KAWAMURA INSTITUTE OF CHEMICAL RESEARCH (JP) 2005-10-26 EP disclosed
US-20050234179-A1 Polymer composite, stretched product thereof and production processes therefor KAWAMURA INSTITUTE OF CHEMICAL RESEARCH. (JP) 2005-10-20 US disclosed