SCHEMBL4369816

SCHEMBL4369816

C#Cc1c(-c2ccccc2)cc(-c2ccccc2)cc1-c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.41
CYP19A1 P11511 1/20 0.41
ALDH1A1 P00352 3/20 0.41
BACE1 P56817 1/20 0.41
CYP2A6 P11509 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
ADORA2A P29274 1/20 0.38
ADORA1 P30542 1/20 0.38
MAPK1 P28482 1/20 0.38
MAPT P10636 2/20 0.37
ATM Q13315 2/20 0.37
HPRT1 P00492 1/20 0.37
PTGS1 P23219 1/20 0.37
SMARCA2 P51531 1/20 0.36
SMARCA4 P51532 1/20 0.36
PBRM1 Q86U86 1/20 0.36
MEN1 O00255 1/20 0.36
APAF1 O14727 1/20 0.36
NPC1 O15118 1/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12679759 0.77 ADORA1 (0.55) ALDH1A1L3MBTL1ADORA2AADORA1MAPK1
SCHEMBL5248607 0.77 PTPN1 (0.46) PTPN1ALDH1A1BACE1L3MBTL1ADORA2A
SCHEMBL29178577 0.77 CYP19A1 (0.38) CYP19A1ALDH1A1BACE1CYP2A6L3MBTL1
SCHEMBL28769199 0.76 CYP19A1 (0.40) CYP19A1ALDH1A1BACE1CYP2A6L3MBTL1
SCHEMBL22064851 0.73 CYP2A6 (0.50) PTPN1ALDH1A1BACE1CYP2A6L3MBTL1
SCHEMBL7789365 0.72 ALDH1A1 (0.56) CYP19A1ALDH1A1BACE1CYP2A6L3MBTL1
SCHEMBL15901560 0.71 BACE1 (0.44) CYP19A1ALDH1A1BACE1CYP2A6L3MBTL1
SCHEMBL16735428 0.71 ALDH1A1 (0.45) CYP19A1ALDH1A1BACE1MAPK1HSD17B10
SCHEMBL8928083 0.70 ALDH1A1 (0.50) PTPN1ALDH1A1BACE1CYP2A6L3MBTL1
SCHEMBL31447556 0.70 CYP19A1 (0.39) CYP19A1ALDH1A1BACE1CYP2A6L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114685741-A Modified bismaleimide resin and preparation method thereof 洛阳尖端技术研究院 2022-07-01 CN disclosed
EP-3078698-B1 POLYARYLENE POLYMERS ROHM & HAAS ELECT MAT (US) 2019-11-20 EP disclosed
US-9752051-B2 Polyarylene polymers ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2017-09-05 US disclosed
EP-3078698-A1 POLYARYLENE POLYMERS Rohm and Haas Electronic Materials LLC (US) 2016-10-12 EP disclosed
US-20160289493-A1 POLYARYLENE POLYMERS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2016-10-06 US disclosed
US-20090247701-A1 COMPOSITION FOR FORMING AN INSULATING FILM FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed