⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16340838 | 0.85 | IDO1 (0.40) | — | |
| SCHEMBL15093316 | 0.76 | IDO1 (0.31) | — | |
| SCHEMBL14964275 | 0.75 | IDO1 (0.32) | — | |
| SCHEMBL14964201 | 0.75 | IDO1 (0.35) | — | |
| SCHEMBL16341406 | 0.75 | IDO1 (0.50) | — | |
| SCHEMBL14964221 | 0.74 | — | — | |
| SCHEMBL14964265 | 0.74 | STAT5B (0.33) | — | |
| SCHEMBL16435075 | 0.74 | — | — | |
| SCHEMBL14964287 | 0.74 | IDO1 (0.31) | — | |
| SCHEMBL16435151 | 0.74 | IDO1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879573-A4 | MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF USING THE SAME | INCYTE CORP (US) | 2009-07-08 | — | — | EP | claimed |
| EP-1879573-A1 | MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF USING THE SAME | Incyte Corporation (US) | 2008-01-23 | — | — | EP | claimed |
| WO-2006122150-A1 | MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF USING THE SAME | INCYTE CORPORATION (US) | 2006-11-16 | — | — | WO | claimed |