Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT5B | P51692 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14964221 | 0.83 | — | — | |
| SCHEMBL16435075 | 0.82 | — | — | |
| SCHEMBL14462414 | 0.82 | POLB (0.38) | STAT5B | |
| SCHEMBL14964339 | 0.80 | MAPK1 (0.32) | STAT5B | |
| SCHEMBL14964324 | 0.80 | IDO1 (0.36) | — | |
| SCHEMBL4982873 | 0.76 | POLB (0.37) | STAT5B | |
| SCHEMBL14461811 | 0.76 | POLB (0.39) | STAT5B | |
| SCHEMBL4982860 | 0.76 | POLB (0.37) | STAT5B | |
| SCHEMBL16340838 | 0.74 | IDO1 (0.40) | — | |
| SCHEMBL4369895 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8951536-B2 | N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase | INCYTE CORPORATION (US) | 2015-02-10 | — | — | US | claimed |
| US-8450351-B2 | N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase | INCYTE CORPORATION (US) | 2013-05-28 | — | — | US | claimed |