Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 13/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2517582 | 0.83 | IDO1 (1.00) | IDO1ALDH1A1MAPTTDO2LMNA | |
| SCHEMBL4540245 | 0.74 | IDO1 (0.54) | IDO1TDO2LMNAPOLBHPGD | |
| SCHEMBL2516757 | 0.73 | IDO1 (0.81) | IDO1MAPTTDO2LMNAPOLB | |
| SCHEMBL4369902 | 0.72 | HIF1A (0.39) | IDO1ALDH1A1MAPTLMNAPOLB | |
| SCHEMBL4369896 | 0.72 | HIF1A (0.39) | IDO1ALDH1A1MAPTLMNAPOLB | |
| SCHEMBL2512502 | 0.71 | IDO1 (0.77) | IDO1MAPTTDO2LMNAPOLB | |
| SCHEMBL2512491 | 0.71 | IDO1 (0.77) | IDO1ALDH1A1MAPTTDO2LMNA | |
| SCHEMBL2520395 | 0.68 | IDO1 (0.72) | IDO1ALDH1A1MAPTTDO2LMNA | |
| SCHEMBL2514961 | 0.68 | IDO1 (0.72) | IDO1ALDH1A1MAPTTDO2LMNA | |
| SCHEMBL2515416 | 0.67 | IDO1 (0.71) | IDO1MAPTTDO2LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879573-A4 | MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF USING THE SAME | INCYTE CORP (US) | 2009-07-08 | — | — | EP | claimed |
| EP-1879573-A1 | MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF USING THE SAME | Incyte Corporation (US) | 2008-01-23 | — | — | EP | claimed |
| WO-2006122150-A1 | MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF USING THE SAME | INCYTE CORPORATION (US) | 2006-11-16 | — | — | WO | claimed |