Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 18/20 | 0.54 |
| ▸ | TDO2 | P48775 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2518277 | 0.85 | IDO1 (0.74) | IDO1TDO2HTTGFERLMNA | |
| SCHEMBL4540239 | 0.76 | ALDH1A1 (0.41) | HTTLMNAHPGD | |
| SCHEMBL4540243 | 0.76 | ALDH1A1 (0.41) | HTTLMNAHPGD | |
| SCHEMBL2519342 | 0.75 | IDO1 (0.74) | IDO1TDO2HTTGFERLMNA | |
| SCHEMBL4369904 | 0.74 | IDO1 (0.71) | IDO1TDO2HTTGFERLMNA | |
| SCHEMBL4368299 | 0.73 | IDO1 (0.66) | IDO1TDO2 | |
| SCHEMBL2520579 | 0.73 | IDO1 (0.79) | IDO1TDO2HTTGFERLMNA | |
| SCHEMBL2514020 | 0.73 | HTT (0.73) | IDO1TDO2HTTGFERLMNA | |
| SCHEMBL2516041 | 0.71 | IDO1 (0.73) | IDO1TDO2HTTGFERLMNA | |
| SCHEMBL19808082 | 0.70 | IDO1 (1.00) | IDO1TDO2HTTGFERLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879573-A4 | MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF USING THE SAME | INCYTE CORP (US) | 2009-07-08 | — | — | EP | claimed |
| EP-1879573-A1 | MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF USING THE SAME | Incyte Corporation (US) | 2008-01-23 | — | — | EP | claimed |
| WO-2006122150-A1 | MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF USING THE SAME | INCYTE CORPORATION (US) | 2006-11-16 | — | — | WO | claimed |