SCHEMBL4370178

SCHEMBL4370178

C=C(C(=O)OCCCC)C(C)N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.50
ALDH1A1 P00352 2/20 0.45
HPGD P15428 2/20 0.44
ATM Q13315 1/20 0.42
HCAR2 Q8TDS4 1/20 0.38
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
PDE4D Q08499 1/20 0.38
NAAA Q02083 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
RAB9A P51151 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
MAPT P10636 1/20 0.37
NPC1 O15118 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
SLC15A1 P46059 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2818114 0.89 TSHR (0.40) TSHRALDH1A1HPGDHCAR2LMNA
SCHEMBL6200579 0.85 TSHR (0.53) TSHRALDH1A1HPGDATMHCAR2
SCHEMBL27506110 0.84 TSHR (0.49) TSHRALDH1A1HPGDATMHCAR2
SCHEMBL7123449 0.83 TSHR (0.52) TSHRALDH1A1HPGDATMHCAR2
SCHEMBL5248798 0.83 TSHR (0.52) TSHRALDH1A1HPGDATMHCAR2
SCHEMBL6658726 0.81 TSHR (0.50) TSHRALDH1A1HPGDATMHCAR2
SCHEMBL6662257 0.81 TSHR (0.50) TSHRALDH1A1HPGDATMHCAR2
SCHEMBL3080867 0.81 TSHR (0.53) TSHRALDH1A1HPGDATMHCAR2
SCHEMBL1492431 0.80 ALDH1A1 (0.45) TSHRALDH1A1LMNACYP1A2CYP2C19
SCHEMBL9066690 0.80 TSHR (0.45) TSHRALDH1A1HPGDATMHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101535215-A Liquid-repellant and stain-resistant cementitious product DU PONT (US) 2009-09-16 CN claimed
EP-1242553-B1 USE OF AN ADDITIVE FOR REGULATING THE SILICONE/ADHESIVE RELEASE FORCE AT THE INTERFACE OF A HEAT-CURABLE SILICONE/ADHESIVE COMPLEX RHODIA CHIMIE SA (FR) 2006-05-10 EP claimed
EP-4366685-A1 COMPOSITIONS AND METHODS FOR IMPROVING THE PHYSICAL PROPERTIES OF HEALTHY AND DAMAGED HAIR Kevin Murphy Group Pty. Ltd. (AU) 2024-05-15 EP disclosed
WO-2023281310-A1 COMPOSITIONS AND METHODS FOR IMPROVING THE PHYSICAL PROPERTIES OF HEALTHY AND DAMAGED HAIR KEVIN MURPHY GROUP PTY. LTD. (AU) 2023-01-12 WO disclosed
CN-103221436-B The approach of polyacrylic ester COLOPLAST A/S (DK) 2015-09-09 CN disclosed
CN-102585121-B Block polymer capable of being used as white board pen ink dispersing agent and white board pen ink CAS GUANGZHOU CHEMISTRY CO LTD 2014-04-02 CN disclosed
CN-103221436-A New routes to polyacrylates COLOPLAST AS 2013-07-24 CN disclosed
CN-101010290-B Diimmonium compound and use thereof NIPPON KAYAKU KK 2011-08-03 CN disclosed
CN-101103081-B Emulsion for aqueous inkjet ink JSR CORP 2010-11-10 CN disclosed
CN-100567401-C Easily dispersible pigment composition CIBA SC HOLDING AG (CH) 2009-12-09 CN disclosed
EP-1982840-B1 Heat-sensitive transfer sheet and image-forming method FUJIFILM CORP (JP) 2009-11-18 EP disclosed
CN-1751102-A Easily dispersible pigment composition CIBA SC HOLDING AG (CH) 2006-03-22 CN disclosed
CN-1643098-A Adhesive film for protection of semiconductor wafer surface and method of protecting semiconductor wafer with the adhesive film MITSUI CHEMICALS INC (JP) 2005-07-20 CN disclosed
US-20040198880-A1 Floor polish composition JOHNSONDIVERSEY, INC. 2004-10-07 US disclosed
EP-1406981-A1 FLOOR POLISH COMPOSITION JohnsonDiversey, Inc. (US) 2004-04-14 EP disclosed
WO-2003002678-A1 FLOOR POLISH COMPOSITION JOHNSONDIVERSEY, INC. (US) 2003-01-09 WO disclosed
CN-1385482-A Aqueous paint compositions and floor polishing compositions JSR K K (JP) 2002-12-18 CN disclosed
CN-1165864-A Method of treating leather with amphoteric polymers ROHM & HAAS (US) 1997-11-26 CN disclosed
US-5134175-A Rapid curing high solids mixture of unsaturated prepolymers and monomers, photoinitiators, fillers, surfactants; for protective coatings, printing inks MLT/MICRO-LITE TECHNOLOGY CORPORATION 1992-07-28 US disclosed
US-3950284-A VINYL POLYMERS, GRAFT OR BLOCK POLYMERS TORAY INDUSTRIES, INC. (JA) 1976-04-13 US disclosed