Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | ATM | Q13315 | 4/20 | 0.61 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.61 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | PABPC1 | P11940 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | APAF1 | O14727 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9397263 | 0.91 | CYP1B1 (0.60) | MEN1KMT2AATMCYP1B1USP2 | |
| SCHEMBL9394455 | 0.89 | CYP1B1 (0.58) | MEN1KMT2AATMCYP1B1USP2 | |
| SCHEMBL13950027 | 0.88 | KDM4E (0.51) | MEN1KMT2AATMCYP1B1USP2 | |
| SCHEMBL27578525 | 0.86 | RAB9A (0.59) | MEN1KMT2AATMCYP1B1USP2 | |
| SCHEMBL31540928 | 0.86 | RAB9A (0.59) | MEN1KMT2AATMCYP1B1USP2 | |
| SCHEMBL12235632 | 0.85 | CYP1B1 (0.58) | MEN1KMT2AATMCYP1B1USP2 | |
| SCHEMBL14560520 | 0.83 | MAPT (0.63) | MEN1KMT2AATMUSP2KDM4E | |
| SCHEMBL13142988 | 0.81 | DPP4 (0.51) | MEN1KMT2AATMKEAP1NFE2L2 | |
| SCHEMBL10451189 | 0.80 | KDM4E (0.59) | MEN1KMT2AATMCYP1B1USP2 | |
| SCHEMBL17212042 | 0.80 | CYP1B1 (0.56) | MEN1KMT2AATMCYP1B1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118596-A2 | PHTHALIMIDE DERIVATIVES AS TRPA1 MODULATORS | GLENMARK PHARMACEUTICALS, S. A. (CH) | 2009-10-01 | — | — | WO | disclosed |
| US-5290921-A | Intermediates and colorants having primary hydroxyl enriched poly (oxyalkylene) moieties and their preparation | MILLIKEN RESEARCH CORPORATION (US) | 1994-03-01 | — | — | US | disclosed |
| US-4324719-A | YELLOW TO BLUE SHADES ON NYLON CARPET | EASTMAN KODAK COMPANY (US) | 1982-04-13 | — | — | US | disclosed |
| US-4039522-A | Phthalimidyl-azo-m-acylamido-n-substituted aniline compounds and polyester fibers dyed therewith | EASTMAN KODAK COMPANY (US) | 1977-08-02 | — | — | US | disclosed |
| US-4012372-A | MONOAZO DISPERSE DYES | EASTMAN KODAK COMPANY (US) | 1977-03-15 | — | — | US | disclosed |
| US-3980634-A | Phthalimidyl-azo aniline type compounds and polyester fibers dyed therewith | EASTMAN KODAK COMPANY (US) | 1976-09-14 | — | — | US | disclosed |