SCHEMBL4372435

SCHEMBL4372435

C=COC(CC)C[SiH](OC)OC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4374685 0.83
SCHEMBL4605926 0.78
SCHEMBL6547492 0.77
SCHEMBL29082791 0.75
SCHEMBL106694 0.74 TSHR (0.35)
SCHEMBL5435746 0.73 THRB (0.33)
SCHEMBL28532870 0.71
SCHEMBL14118016 0.70
SCHEMBL27298744 0.70
SCHEMBL237322 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1383470-B1 HAIR TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2009-06-17 EP disclosed
EP-1383469-B1 HAIR TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2006-02-15 EP disclosed
EP-1383860-B1 FABRIC CARE COMPOSITIONS UNILEVER PLC (GB) 2005-10-12 EP disclosed
US-6696051-B2 CONTAINING CORE PARTICLES HAVING A D3,2 AVERAGE PARTICLE SIZE OF 10-700 NM, AND COATED WITH COVALENTLY BONDED SILICONE POLYMER UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-02-24 US disclosed
US-6696050-B2 COATED PARTICLES COMPRISING (A) A SOLID CORE HAVING A D3, 2 AVERAGE PARTICLE SIZE IN THE RANGE FROM 10 TO 700 NM, AND (B) A COATING POLYMER COVALENTLY BONDED TO THE SOLID CORE; E.G., SOLID SILICA CORES AND POLYSTYRENE COATING POLYMER UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-02-24 US disclosed
US-20030095943-A1 Hair treatment compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-05-22 US disclosed
US-20030012757-A1 Hair treatment compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-01-16 US disclosed
EP-0433727-B1 Silica-core silicone-shell particles, emulsion containing the same dispersed therein, and process for producing the emulsion TOSHIBA SILICONE (JP) 1995-08-02 EP disclosed
EP-0433906-B1 Thermoplastic resin and process for producing the same TOSHIBA SILICONE (JP) 1995-07-26 EP disclosed
US-5218014-A Graft polymer formed by graft polymerization of vinyl monomer onto colloidal silica core silicone shell particles TOSHIBA SILICONE CO., LTD. (JP) 1993-06-08 US disclosed
US-5188899-A SILICA-CORE SILICONE-SHELL PARTICLES, EMULSION CONTAINING THE SAME DISPERSED THEREIN, AND PROCESS FOR PRODUCING THE EMULSION TOSHIBA SILICONE CO., LTD. (JP) 1993-02-23 US disclosed
EP-0433906-A2 Thermoplastic resin and process for producing the same TOSHIBA SILICONE CO., LTD. (JP) 1991-06-26 EP disclosed
EP-0433727-A1 Silica-core silicone-shell particles, emulsion containing the same dispersed therein, and process for producing the emulsion TOSHIBA SILICONE CO., LTD. (JP) 1991-06-26 EP disclosed