SCHEMBL4372500

SCHEMBL4372500

COC(=O)C(C)CS(=O)(=O)O

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA14 Q9ULX7 5/20 0.45
CA12 O43570 4/20 0.42
SMN1; SMN2 Q16637 2/20 0.38
CA7 P43166 2/20 0.38
CA9 Q16790 2/20 0.38
KMT2A Q03164 4/20 0.35
MEN1 O00255 3/20 0.35
PTPRB P23467 1/20 0.34
SLC22A6 Q4U2R8 1/20 0.33
MME P08473 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
GRIA1 P42261 3/20 0.32
ESRRB O95718 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL575986 0.84 SLC22A6 (0.34) CA14CA12SLC22A6
SCHEMBL2591216 0.80 CA14 (0.43) CA14CA12SMN1; SMN2CA7CA9
SCHEMBL4904213 0.80 CA14 (0.43) CA14CA12SMN1; SMN2CA7CA9
SCHEMBL4372490 0.80 CA14 (0.43) CA14CA12SMN1; SMN2CA7CA9
SCHEMBL31247919 0.80 CA14 (0.43) CA14CA12SMN1; SMN2CA7CA9
SCHEMBL19963061 0.77 CA14 (0.40) CA14CA12SMN1; SMN2CA7CA9
SCHEMBL575987 0.77 NAAA (0.31) SLC22A6
SCHEMBL16369139 0.77 CA12 (0.38) CA14CA12CA7KMT2ASLC22A6
SCHEMBL3766175 0.76 CA14 (0.39) CA14CA12SMN1; SMN2CA7CA9
SCHEMBL1786590 0.76 CA14 (0.39) CA14CA12SMN1; SMN2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1592733-B1 MICROSPHERES AKZO NOBEL NV (NL) 2009-07-08 EP claimed
CN-100354346-C Microspheres AKZO NOBEL NV (NL) 2007-12-12 CN claimed
CN-1738853-A Microspheres AKZO NOBEL NV (NL) 2006-02-22 CN claimed
EP-1592733-A1 MICROSPHERES Akzo Nobel N.V. (NL) 2005-11-09 EP claimed
US-20040249005-A1 eliminating residual monomers such as (meth)acrylonitrile from thermoplastic expandable microspheres of a thermoplastic polymer shell encapsulating a propellant, by contacting with oxo acids of sulfur such as a bisulfite to form 2-cyano-ethanesulfonic acid for example AKZO NOBEL N.V. (NL) 2004-12-09 US claimed
WO-2004072160-A1 MICROSPHERES AKZO NOBEL N.V. (NL) 2004-08-26 WO claimed
EP-1592733-B1 MICROSPHERES AKZO NOBEL NV (NL) 2009-07-08 EP disclosed
CN-100354346-C Microspheres AKZO NOBEL NV (NL) 2007-12-12 CN disclosed
CN-1738853-A Microspheres AKZO NOBEL NV (NL) 2006-02-22 CN disclosed
EP-1592733-A1 MICROSPHERES Akzo Nobel N.V. (NL) 2005-11-09 EP disclosed
US-20040249005-A1 eliminating residual monomers such as (meth)acrylonitrile from thermoplastic expandable microspheres of a thermoplastic polymer shell encapsulating a propellant, by contacting with oxo acids of sulfur such as a bisulfite to form 2-cyano-ethanesulfonic acid for example AKZO NOBEL N.V. (NL) 2004-12-09 US disclosed
WO-2004072160-A1 MICROSPHERES AKZO NOBEL N.V. (NL) 2004-08-26 WO disclosed
CN-1096448-C Farnesyl transferase inhibitors, its preparation and medicine composition thereof RHONE POULENC RORER SA (FR) 2002-12-18 CN disclosed
CN-1190389-A Novel farnesyl transferase inhibitors, process for their preparation and pharmaceutical compositions containing them RHONE POULENC RORER SA (FR) 1998-08-12 CN disclosed