Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | HPGD | P15428 | 5/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.63 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | CLK2 | P49760 | 1/20 | 0.63 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9155488 | 0.86 | KCNH2 (0.66) | KDM4EALDH1A1HPGDKCNH2HSD17B10 | |
| SCHEMBL9155786 | 0.86 | KCNH2 (0.66) | KDM4EALDH1A1HPGDKCNH2HSD17B10 | |
| SCHEMBL1155026 | 0.85 | KDM4E (0.80) | KDM4EALDH1A1HPGDKCNH2HSD17B10 | |
| SCHEMBL5571225 | 0.85 | KDM4E (0.71) | KDM4EALDH1A1HPGDKCNH2HSD17B10 | |
| Hydrochloric Acid SCHEMBL9751979 | 0.84 | KDM4E (0.79) | KDM4EALDH1A1HPGDKCNH2HSD17B10 | |
| Water SCHEMBL27625917 | 0.84 | KDM4E (0.79) | KDM4EALDH1A1HPGDKCNH2HSD17B10 | |
| SCHEMBL28079403 | 0.84 | KDM4E (0.79) | KDM4EALDH1A1HPGDKCNH2HSD17B10 | |
| Water SCHEMBL28828205 | 0.84 | KDM4E (0.79) | KDM4EALDH1A1HPGDKCNH2HSD17B10 | |
| Methyl Alcohol SCHEMBL29163210 | 0.84 | KDM4E (0.79) | KDM4EALDH1A1HPGDKCNH2HSD17B10 | |
| SCHEMBL27918942 | 0.84 | KDM4E (0.79) | KDM4EALDH1A1HPGDKCNH2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009064792-A1 | QUINOLONE CARBOXYLIC ACID-SUBSTITUTED RIFAMYCIN DERIVATIVES | CUMBRE PHARMACEUTICALS INC. (US) | 2009-05-22 | — | — | WO | disclosed |