Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.60 |
| ▸ | FPR2 | P25090 | 1/20 | 0.60 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.57 |
| ▸ | CTSL | P07711 | 4/20 | 0.56 |
| ▸ | CTSS | P25774 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11765285 | 0.93 | CA2 (0.62) | PTPN1CA2HDAC3HDAC4HDAC1 | |
| SCHEMBL9461988 | 0.93 | PTPN1 (0.73) | PTPN1CA2HDAC3HDAC4HDAC1 | |
| SCHEMBL9461443 | 0.93 | PTPN1 (0.73) | PTPN1CA2HDAC3HDAC4HDAC1 | |
| SCHEMBL9461442 | 0.93 | PTPN1 (0.73) | PTPN1CA2HDAC3HDAC4HDAC1 | |
| SCHEMBL11582404 | 0.92 | CA2 (0.63) | PTPN1CA2HDAC3HDAC4HDAC1 | |
| SCHEMBL11582403 | 0.92 | CA2 (0.63) | PTPN1CA2HDAC3HDAC4HDAC1 | |
| SCHEMBL11765307 | 0.91 | CA2 (0.65) | PTPN1CA2HDAC3HDAC4HDAC1 | |
| SCHEMBL4360736 | 0.91 | GAA (0.67) | PTPN1CA2HDAC3HDAC4HDAC1 | |
| SCHEMBL3719426 | 0.90 | CA2 (0.72) | PTPN1CA2FPR2KMT2AITGB3 | |
| SCHEMBL3719424 | 0.90 | CA2 (0.72) | PTPN1CA2FPR2KMT2AITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247470-A1 | PHENYLALANINE DIPEPTIDE DERIVATIVES, COMPOSITIONS AND USE THEREOF | The Key Lab. Of Chemistry for Natural Products of Guizhou Province and Chinese Acad. of Sciences (CN) | 2009-10-01 | — | — | US | claimed |
| US-9023809-B2 | Phenylalanine dipeptide derivatives, compositions and use thereof | THE KEY LABORATORY OF CHEMISTRY FOR NATURAL PRODUCTS OF GUIZHOU PROVINCE AND CHINESE ACADEMY OF SCIENCES (CN) | 2015-05-05 | — | — | US | disclosed |
| US-20090247470-A1 | PHENYLALANINE DIPEPTIDE DERIVATIVES, COMPOSITIONS AND USE THEREOF | The Key Lab. Of Chemistry for Natural Products of Guizhou Province and Chinese Acad. of Sciences (CN) | 2009-10-01 | — | — | US | disclosed |
| CN-100480234-C | N-(N-benzoyl-phenylalanyl)-phenylalanine dipeptide derivative, and preparing method and use thereof | KEY LAB OF CHEMISTRY FOR NATUR (CN) | 2009-04-22 | — | — | CN | disclosed |
| CN-1935779-A | N-(N-benzoyl-phenylalanyl)-phenylalanine dipeptide derivative, and its preparing method and use | NATURAL PRODUCT CHEMISTRY KEY (CN) | 2007-03-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247470-A1 | PHENYLALANINE DIPEPTIDE DERIVATIVES, COMPOSITIONS AND USE THEREOF | DNPEP, PEPD, VIP | PTPN1 1817/4885CA2 4136/4885HDAC3 4763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.