Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.39 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10163768 | 0.85 | HDAC1 (0.49) | CACNA1HCACNA1BCACNA1CL3MBTL1GRM2 | |
| SCHEMBL29726447 | 0.84 | CACNA1H (0.46) | CACNA1HCACNA1BCACNA1CL3MBTL1GRM2 | |
| SCHEMBL15385130 | 0.83 | CACNA1H (0.46) | CACNA1HCACNA1BCACNA1CL3MBTL1GRM2 | |
| SCHEMBL23273951 | 0.82 | CACNA1H (0.44) | CACNA1HCACNA1BCACNA1CL3MBTL1GRM2 | |
| SCHEMBL10232987 | 0.82 | BRD9 (0.48) | CACNA1HCACNA1BCACNA1CL3MBTL1GRM2 | |
| SCHEMBL24970178 | 0.82 | NOTUM (0.48) | CACNA1HCACNA1BCACNA1CL3MBTL1GRM2 | |
| SCHEMBL1726030 | 0.82 | CACNA1H (0.46) | CACNA1HCACNA1BCACNA1CL3MBTL1GRM2 | |
| SCHEMBL31142856 | 0.82 | NOTUM (0.48) | CACNA1HCACNA1BCACNA1CL3MBTL1GRM2 | |
| SCHEMBL23274113 | 0.81 | RXRA (0.48) | CACNA1HCACNA1BCACNA1C | |
| SCHEMBL8247726 | 0.79 | CACNA1H (0.43) | CACNA1HCACNA1BCACNA1CL3MBTL1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |