SCHEMBL43735

SCHEMBL43735

COc1cccc(C(C)O)c1

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 3/20 0.57
L3MBTL1 Q9Y468 1/20 0.56
CASR P41180 2/20 0.50
CHRM2 P08172 1/20 0.50
CHRM1 P11229 1/20 0.50
CHRM3 P20309 1/20 0.50
UGT2B7 P16662 1/20 0.48
ACHE P22303 1/20 0.48
POLB P06746 1/20 0.48
TSHR P16473 1/20 0.47
MAPK1 P28482 1/20 0.47
TAAR1 Q96RJ0 2/20 0.47
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL343726 1.00 AOC3 (0.57) AOC3L3MBTL1CASRCHRM2CHRM1
SCHEMBL43520 1.00 AOC3 (0.57) AOC3L3MBTL1CASRCHRM2CHRM1
SCHEMBL2608969 0.86 AOC3 (0.58) AOC3L3MBTL1CASRCHRM2CHRM1
SCHEMBL6912472 0.85 PTGS1 (0.58) AOC3L3MBTL1UGT2B7ACHE
SCHEMBL6912468 0.85 PTGS1 (0.58) AOC3L3MBTL1UGT2B7ACHE
SCHEMBL2093768 0.85 AOC3 (0.59) AOC3L3MBTL1CASRCHRM2CHRM1
SCHEMBL2087869 0.85 AOC3 (0.59) AOC3L3MBTL1CASRCHRM2CHRM1
SCHEMBL11604883 0.85 AOC3 (0.62) AOC3L3MBTL1CASRCHRM2CHRM1
SCHEMBL24925808 0.84 AOC3 (0.54) AOC3L3MBTL1CASRCHRM2CHRM1
SCHEMBL18793772 0.84 AOC3 (0.54) AOC3L3MBTL1CASRCHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122011028-A Method for efficiently preparing various substituted chiral phosphoramides 上海交通大学 2026-05-12 CN claimed
CN-114292385-B Nitrogen-containing porous organic polymer composite material and preparation method and application thereof 苏州大学 2023-09-05 CN claimed
WO-2023123126-A1 NITROGEN-CONTAINING POROUS ORGANIC POLYMER COMPOSITE MATERIAL AND PREPARATION METHOD AND APPLICATION THEREOF 苏州大学 2023-07-06 WO claimed
CN-110002961-B Method for racemization-free synthesis of chiral alcohol 三峡大学 2022-05-03 CN claimed
CN-114292385-A Nitrogen-containing porous organic polymer composite material and preparation method and application thereof 苏州大学 2022-04-08 CN claimed
CN-110144139-B Zinc oxide-based nanoparticle ink and photoelectric device 纳晶科技股份有限公司 2022-01-18 CN claimed
US-20200384451-A1 PHOSPHINE FREE COBALT BASED CATALYST, PROCESS FOR PREPARATION AND USE THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2020-12-10 US claimed
CN-101580482-A Method for preparing rivastigmine hydrogen tartrate and application thereof UNIV SHENYANG PHARMACEUTICAL (CN) 2009-11-18 CN claimed
US-6613317-B1 In particular northern corn rootworm THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2003-09-02 US claimed
CN-122011028-A Method for efficiently preparing various substituted chiral phosphoramides 上海交通大学 2026-05-12 CN disclosed
CN-120040353-A Nitrogen-containing heteroaryl compound, and preparation method and application thereof 江苏恩华药业股份有限公司 2025-05-27 CN disclosed
CN-119798058-A Preparation method of alpha-alkyl ketone derivative 浙江工业大学 2025-04-11 CN disclosed
CN-119491240-A Method for preparing benzyl carboxylic acid compound by taking carbon dioxide as raw material 哈尔滨工业大学(深圳) 2025-02-21 CN disclosed
CN-116693467-B Thiazole amine MBL inhibitor and preparation method and application thereof 四川大学 2025-02-14 CN disclosed
US-5238938-A Nephrosis OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-08-24 US disclosed
EP-0411150-A1 INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-02-06 EP disclosed
EP-0371733-A2 Dopamine-beta-hydroxylase inhibitors SMITHKLINE BEECHAM CORPORATION (US) 1990-06-06 EP disclosed
EP-0149976-A2 Substituted imidazoles CIBA-GEIGY AG (CH) 1985-07-31 EP disclosed
US-4346242-A Method for preparing substituted meta-phenylalkoxynitrobenzenes AMERICAN CYANAMID COMPANY (US) 1982-08-24 US disclosed
US-4094994-A ANTICANCER AGENTS, TUMOR INHIBITION, HORMONE-DEPENDENT CARCINOMAS KLINGE PHARMA GMBH (DT) 1978-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200384451-A1 PHOSPHINE FREE COBALT BASED CATALYST, PROCESS FOR PREPARATION AND USE THEREOF CPNE4, PPOX, PDCD5 AOC3 853/4885L3MBTL1 4818/4885CASR 4183/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.