Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 12/20 | 0.72 |
| ▸ | BCR | P11274 | 10/20 | 0.72 |
| ▸ | PRKCA | P17252 | 4/20 | 0.70 |
| ▸ | EGFR | P00533 | 5/20 | 0.68 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.68 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.65 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.65 |
| ▸ | KIT | P10721 | 1/20 | 0.60 |
| ▸ | JAK3 | P52333 | 1/20 | 0.60 |
| ▸ | BTK | Q06187 | 1/20 | 0.60 |
| ▸ | ITK | Q08881 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.58 |
| ▸ | CDK1 | P06493 | 1/20 | 0.58 |
| ▸ | RET | P07949 | 1/20 | 0.58 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.58 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22628286 | 0.86 | ABL1 (0.70) | ABL1BCRPRKCAEGFRPRKCD | |
| SCHEMBL12320924 | 0.86 | ABL1 (0.78) | ABL1BCRPRKCAEGFRPDGFRB | |
| SCHEMBL3085556 | 0.85 | ABL1 (0.66) | ABL1BCRPRKCAEGFRPRKCD | |
| SCHEMBL7475168 | 0.85 | CCNB2 (0.55) | ABL1BCRPRKCAEGFRPRKCD | |
| SCHEMBL7462310 | 0.84 | ABL1 (0.68) | ABL1BCRPRKCAEGFRPRKCD | |
| SCHEMBL2392 | 0.84 | ABL1 (1.00) | ABL1BCRPRKCAEGFRPDGFRB | |
| SCHEMBL29005835 | 0.84 | ABL1 (0.75) | ABL1BCRPRKCAEGFRPDGFRB | |
| SCHEMBL3860532 | 0.84 | ABL1 (0.83) | ABL1BCRPRKCAEGFRPRKCD | |
| SCHEMBL29366999 | 0.84 | ABL1 (1.00) | ABL1BCRPRKCAEGFRPDGFRB | |
| SCHEMBL3210634 | 0.84 | ABL1 (0.75) | ABL1BCRPRKCAEGFRPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066350-A1 | CRBN E3 LIGASE LIGAND COMPOUND, PROTEIN DEGRADING AGENT DEVELOPED ON THE BASIS OF LIGAND COMPOUND, AND THEIR APPLICATIONS | 标新生物医药科技(上海)有限公司 | 2023-04-27 | — | — | WO | claimed |
| WO-2009109991-A2 | NOVEL HYDRAZIDE CONTAINING TYROSINE KINASE INHIBITORS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD., (IN) | 2009-09-11 | — | — | WO | disclosed |
| WO-2009109991-A2 | NOVEL HYDRAZIDE CONTAINING TYROSINE KINASE INHIBITORS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD., (IN) | 2009-09-11 | — | — | WO | disclosed |