Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.31 |
| ▸ | SMPD2 | O60906 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11151572 | 1.00 | ALDH1A1 (0.34) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL500663 | 0.98 | KMT2A (0.33) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL27738300 | 0.98 | KMT2A (0.33) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL500664 | 0.98 | KMT2A (0.33) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL14950974 | 0.83 | ALDH1A1 (0.34) | ALDH1A1KMT2AMEN1DPP4 | |
| SCHEMBL2550190 | 0.80 | SMPD2 (0.41) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL607777 | 0.80 | ALDH1A1 (0.35) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL27505903 | 0.79 | KMT2A (0.33) | ALDH1A1KMT2AMEN1KDM4ESMPD2 | |
| SCHEMBL27669545 | 0.79 | KMT2A (0.33) | ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL28106794 | 0.78 | TP53 (0.36) | ALDH1A1KMT2AMEN1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-10751337-B2 | Preservative free ocular compositions and methods for using the same for treating dry eye disease and other eye disorders | Ocugen, Inc. (US) | 2020-08-25 | — | — | US | disclosed |
| EP-3569223-A1 | METHODS AND COMPOSITIONS FOR SUSTAINED DELIVERY OF DRUGS | Intratus, Inc. (US) | 2019-11-20 | — | — | EP | disclosed |
| EP-2493474-B1 | METHODS AND COMPOSITIONS FOR SUSTAINED DELIVERY OF DRUGS | INTRATUS INC (US) | 2019-09-04 | — | — | EP | disclosed |
| US-20180221278-A1 | PRSUSTAINED RELEASE OPTHALMIC FORMUATION AND METHODS FOR USING THE SAME | Ocugen, Inc. (US) | 2018-08-09 | — | — | US | disclosed |
| US-20180153885-A1 | PRESERVATIVE FREE OCULAR COMPOSITIONS AND METHODS FOR USING THE SAME FOR TREATING DRY EYE DISEASE AND OTHER EYE DISORDERS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-06-07 | — | — | US | disclosed |
| US-9877964-B2 | Methods and compositions for treating dry eye disease and other eye disorders | Ocugen, Inc. (US) | 2018-01-30 | — | — | US | disclosed |
| EP-3261620-A1 | METHODS AND COMPOSITIONS FOR TREATING DRY EYE DISEASE AND OTHER EYE DISORDERS | The Board of Trustees of the University of Illionis (US) | 2018-01-03 | — | — | EP | disclosed |
| US-20170189396-A1 | METHODS AND COMPOSITIONS FOR TREATING DRY EYE DISEASE AND OTHER EYE DISORDERS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2017-07-06 | — | — | US | disclosed |
| US-9597328-B2 | Methods and compositions for treating dry eye disease and other eye disorders | Ocugen, Inc. (US) | 2017-03-21 | — | — | US | disclosed |
| EP-1754491-A1 | OPHTHALMIC PERCUTANEOUSLY ABSORBED PREPARATION CONTAINING MUSCARINIC RECEPTOR AGONIST | Senju Pharmaceutical Co., Ltd. (JP) | 2007-02-21 | — | — | EP | disclosed |
| WO-2007007863-A1 | PERCUTANEOUSLY ABSORPTIVE OPHTHALMIC PREPARATION COMPRISING OLOPATADINE | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2007-01-18 | — | — | WO | disclosed |
| WO-2007007851-A1 | PERCUTANEOUSLY ABSORPTIVE OPHTHALMIC PREPARATION COMPRISING EPINASTINE | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2007-01-18 | — | — | WO | disclosed |
| CN-1819846-A | Ophthalmic percutaneously absorbed preparation containing muscarinic receptor agonist | SENJU PHARMA CO (JP) | 2006-08-16 | — | — | CN | disclosed |
| US-6660045-B1 | Hair colorant preparation | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2003-12-09 | — | — | US | disclosed |
| EP-1098871-B1 | alpha-AMINO ACID PHENYL ESTER DERIVATIVES | AKZO NOBEL NV (NL) | 2003-07-09 | — | — | EP | disclosed |
| US-6451854-B1 | α-amino acid phenyl ester derivatives | AKZO NOBEL N.V. (NL) | 2002-09-17 | — | — | US | disclosed |
| EP-1098871-A1 | $g(a)-AMINO ACID PHENYL ESTER DERIVATIVES | Akzo Nobel N.V. (NL) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000005196-A1 | α-AMINO ACID PHENYL ESTER DERIVATIVES | AKZO NOBEL N.V. (NL) | 2000-02-03 | — | — | WO | disclosed |
| US-4396400-A | WATER, NITROGENOUS CARBOXYLATE OR SULFONATE SURFACTANT | SOCIETE ELF FRANCE (FR) | 1983-08-02 | — | — | US | disclosed |