Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.61 |
| ▸ | ACHE | P22303 | 5/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.57 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.57 |
| ▸ | KDM4A | O75164 | 2/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4332580 | 0.90 | NPC1 (0.51) | BCHEACHEHDAC3HDAC1HDAC2 | |
| SCHEMBL1667586 | 0.82 | ALOX5 (0.69) | HDAC3HDAC1HDAC2HDAC8KDM4A | |
| SCHEMBL4802333 | 0.81 | NPC1 (0.51) | ACHEKDM4AKDM4CNPC1RAB9A | |
| SCHEMBL829335 | 0.80 | ALOX5 (0.61) | HDAC3HDAC1HDAC2HDAC8KDM4A | |
| SCHEMBL17275348 | 0.80 | NPC1 (0.50) | BCHEACHENPC1RAB9AKMT2A | |
| SCHEMBL9172613 | 0.80 | BCHE (0.61) | BCHEACHEHDAC3HDAC1HDAC2 | |
| SCHEMBL11527785 | 0.78 | HDAC1 (0.71) | BCHEACHEHDAC3HDAC1HDAC2 | |
| SCHEMBL4327317 | 0.78 | HDAC1 (0.71) | BCHEACHEHDAC3HDAC1HDAC2 | |
| SCHEMBL15456409 | 0.77 | HDAC1 (0.71) | BCHEACHEHDAC3HDAC1HDAC2 | |
| SCHEMBL1727025 | 0.77 | KMT2A (0.62) | HDAC2HDAC8NPC1RAB9AALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009114633-A1 | PROCESS FOR THE PREPARATION OF (3S)-3-AMINO-N-CYCLOPROPYL-2-HYDROXYALKANAMIDE DERIVATIVES | VIROBAY, INC. (US) | 2009-09-17 | — | — | WO | disclosed |