SCHEMBL4375192

SCHEMBL4375192

C=CCN(CC=C)ON(CC=C)CC=C

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL11498048 0.78 ALDH1A1 (0.41) ALDH1A1
SCHEMBL8030995 0.76 ALDH1A1 (0.32) ALDH1A1
SCHEMBL7164576 0.73
SCHEMBL6685770 0.73
SCHEMBL10495561 0.73
SCHEMBL16500480 0.73
SCHEMBL6703959 0.71
SCHEMBL527872 0.71 MEN1 (0.30)
SCHEMBL6007857 0.69 ALDH1A1 (0.31) ALDH1A1
SCHEMBL9339493 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0436653-A4 SYNTHESIS OF CAMPTOTHECIN AND ANALOGS THEREOF 1992-01-15 EP claimed
EP-0436653-A1 SYNTHESIS OF CAMPTOTHECIN AND ANALOGS THEREOF RESEARCH TRIANGLE INSTITUTE (US) 1991-07-17 EP claimed
WO-1990003169-A1 SYNTHESIS OF CAMPTOTHECIN AND ANALOGS THEREOF RESEARCH TRIANGLE INSTITUTE (US) 1990-04-05 WO claimed
JP-10331091-A None JP disclosed
WO-2023276967-A1 OSMOREGULATOR 国立大学法人九州大学 2023-01-05 WO disclosed
US-8071642-B2 Dimethyl amino ethyl ether psoralens and methods for their production and use RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2011-12-06 US disclosed
CN-101466725-A Amino derivatives of androstanes and androstenes as medicaments for cardiovascular disorders SIGMA TAU IND FARMACEUTI (IT) 2009-06-24 CN disclosed
US-20090155224-A1 Dimethyl amino ethyl ether psoralens and methods for their production and use RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2009-06-18 US disclosed
WO-2004024671-A1 METHOD FOR THE PRODUCTION OF DIALKYL AMINO ETHERS SASOL GERMANY GMBH (DE) 2004-03-25 WO disclosed
WO-2004024671-A1 METHOD FOR THE PRODUCTION OF DIALKYL AMINO ETHERS SASOL GERMANY GMBH (DE) 2004-03-25 WO disclosed
WO-2004024671-A1 METHOD FOR THE PRODUCTION OF DIALKYL AMINO ETHERS SASOL GERMANY GMBH (DE) 2004-03-25 WO disclosed
EP-0436653-A4 SYNTHESIS OF CAMPTOTHECIN AND ANALOGS THEREOF 1992-01-15 EP disclosed
EP-0436653-A1 SYNTHESIS OF CAMPTOTHECIN AND ANALOGS THEREOF RESEARCH TRIANGLE INSTITUTE (US) 1991-07-17 EP disclosed
US-4981968-A ENZYME INHIBITORS, ANTITUMOR RESEARCH TRIANGLE INSTITUTE (US) 1991-01-01 US disclosed
WO-1990003169-A1 SYNTHESIS OF CAMPTOTHECIN AND ANALOGS THEREOF RESEARCH TRIANGLE INSTITUTE (US) 1990-04-05 WO disclosed
US-4620037-A COSMETICS, PHARMACEUTICALS L'OREAL (FR) 1986-10-28 US disclosed
EP-0158893-A1 Silane containing isocyanate prepolymers UNION CARBIDE CORPORATION (US) 1985-10-23 EP disclosed
US-4491534-A Sequenced surfactant oligomers, process for preparing the same and compositions containing the same L'OREAL (FR) 1985-01-01 US disclosed
US-4199562-A USED IN COSMETICS AND DRUGS L'OREAL (FR) 1980-04-22 US disclosed
US-3838158-A DIALKYLAMINO ETHERS OF BENZOPYRANOPYRIDINES SHARPS ASS 1974-09-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090155224-A1 Dimethyl amino ethyl ether psoralens and methods for their production and use HLA-C, HLA-A, HLA-B ALDH1A1 2269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.