Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PDXK | O00764 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL28550780 | 0.85 | — | — | |
| Formic Acid SCHEMBL28417459 | 0.85 | TDP1 (0.32) | TDP1 | |
| Formic Acid SCHEMBL28550777 | 0.85 | TDP1 (0.32) | TDP1 | |
| SCHEMBL6305842 | 0.81 | HTT (0.40) | DYRK1APIK3CDALDH1A1CYP3A4GAA | |
| SCHEMBL7361765 | 0.79 | DYRK1A (0.41) | DYRK1AALDH1A1CYP3A4PLAUGAA | |
| SCHEMBL7841635 | 0.79 | HTT (0.34) | DYRK1APIK3CDALDH1A1CYP3A4PLAU | |
| SCHEMBL11610661 | 0.75 | PLAU (0.33) | DYRK1APLAU | |
| SCHEMBL22207395 | 0.75 | NOS3 (0.39) | PIK3CDALDH1A1GAA | |
| SCHEMBL22208146 | 0.75 | CHEK1 (0.31) | PIK3CD | |
| SCHEMBL31413296 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119569700-A | 6-Nitrogen-containing cyclopicolinic acid and partial formate compound thereof, and preparation method and application thereof | 中国农业大学 | 2025-03-07 | — | — | CN | disclosed |
| CN-118217896-A | Continuous reaction device and method for continuously preparing 4-amino-3, 5, 6-trichloropyridine nitrile | 北京颖泰嘉和生物科技股份有限公司 | 2024-06-21 | — | — | CN | disclosed |
| US-20240099297-A1 | HIGHLY LOADED EMULSIFIABLE CONCENTRATE FORMULATION OF TRICLOPYR AND PICLORAM | Adama Australia Pty Limited (AU) | 2024-03-28 | — | — | US | disclosed |
| US-20220371997-A1 | PREPARATION OF HALOGEN ANALOGS OF PICLORAM | CORTEVA AGRISCIENCE LLC (US) | 2022-11-24 | — | — | US | disclosed |
| US-11401242-B2 | Preparation of halogen analogs of picloram | CORTEVA AGRISCIENCE LLC (US) | 2022-08-02 | — | — | US | disclosed |
| US-20210323923-A1 | PREPARATION OF HALOGEN ANALOGS OF PICLORAM | CORTEVA AGRISCIENCE LLC (US) | 2021-10-21 | — | — | US | disclosed |
| WO-2020061146-A1 | PREPARATION OF HALOGEN ANALOGS OF PICLORAM | DOW AGROSCIENCES LLC (US) | 2020-03-26 | — | — | WO | disclosed |
| CN-110438522-A | A kind of method that the dechlorination of electrochemistry selectivity prepares 4- amino -3,6- lontrel | UNIV ZHEJIANG TECHNOLOGY | 2019-11-12 | — | — | CN | disclosed |
| CN-105803481-B | A kind of method that catalytic electrolysis prepares the formic acid of 4 amino, 3,6 dichloropyridine 2 | 浙江埃森化学有限公司 | 2018-03-27 | — | — | CN | disclosed |
| CN-104988531-B | The method that a kind of selective dechlorination of chloro-pyridine formic acid electro-catalysis prepares pyridine carboxylic acid | 浙江工业大学 | 2017-11-07 | — | — | CN | disclosed |
| US-7625919-B2 | 4-azasteroid derivatives as androgen receptor modulators | MERCK & CO., INC. (US) | 2009-12-01 | — | — | US | disclosed |
| US-7625919-B2 | 4-azasteroid derivatives as androgen receptor modulators | MERCK & CO., INC. (US) | 2009-12-01 | — | — | US | disclosed |
| US-20090291950-A1 | BICYCLIC HETEROARYL INHIBITORS OF PDE4 | KALYPSYS, INC. (US) | 2009-11-26 | — | — | US | disclosed |
| WO-2008006052-A2 | BICYCLIC HETEROARYL INHIBITORS OF PDE4 | GOVEK STEVEN P (US) | 2008-01-10 | — | — | WO | disclosed |
| US-20070072096-A1 | Negative curable dye-containing composition, color filter, and method of manufacturing the same | FUJI PHOTO FILM CO., LTD. | 2007-03-29 | — | — | US | disclosed |
| CN-1219171-A | Benzofuran carboxamides and their therapeutic use | DARWIN DISCOVERY CO LTD (GB) | 1999-06-09 | — | — | CN | disclosed |
| US-4066438-A | HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1978-01-03 | — | — | US | disclosed |
| US-3883541-A | 4-Amino-3,5,6-trichloro-2-(functionally substituted methyl) pyridine compounds | DOW CHEMICAL CO | 1975-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11401242-B2 | Preparation of halogen analogs of picloram | PBRM1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, PHF6 | DYRK1A 3992/4885PIK3CD 791/4885ALDH1A1 1275/4885 |
| US-20090291950-A1 | BICYCLIC HETEROARYL INHIBITORS OF PDE4 | PDE4A, PDE4B, PDE4C | DYRK1A 3055/4885PIK3CD 1504/4885ALDH1A1 552/4885 |
| US-20210323923-A1 | PREPARATION OF HALOGEN ANALOGS OF PICLORAM | PBRM1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, PHF6 | DYRK1A 3992/4885PIK3CD 791/4885ALDH1A1 1275/4885 |
| US-20220371997-A1 | PREPARATION OF HALOGEN ANALOGS OF PICLORAM | PBRM1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, PHF6 | DYRK1A 3992/4885PIK3CD 791/4885ALDH1A1 1275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.