Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA8 | P11142 | 4/20 | 0.69 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.69 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | HBB | P68871 | 1/20 | 0.63 |
| ▸ | GAPDH | P04406 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.58 |
| ▸ | SLC28A2 | O43868 | 3/20 | 0.56 |
| ▸ | AMD1 | P17707 | 1/20 | 0.56 |
| ▸ | FBP1 | P09467 | 1/20 | 0.55 |
| ▸ | DPP4 | P27487 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.55 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6825727 | 0.93 | HSPA8 (0.73) | HSPA8HSPA5RXFP1SMN1; SMN2LMNA | |
| SCHEMBL5672460 | 0.92 | HSPA8 (0.69) | HSPA8HSPA5RXFP1SMN1; SMN2LMNA | |
| SCHEMBL5672454 | 0.92 | HSPA8 (0.69) | HSPA8HSPA5RXFP1SMN1; SMN2LMNA | |
| SCHEMBL7027923 | 0.92 | HSPA8 (0.72) | HSPA8HSPA5RXFP1SMN1; SMN2LMNA | |
| SCHEMBL6897817 | 0.91 | HSPA8 (0.68) | HSPA8HSPA5RXFP1SMN1; SMN2LMNA | |
| SCHEMBL3074979 | 0.87 | HSPA8 (0.72) | HSPA8HSPA5RXFP1SMN1; SMN2LMNA | |
| SCHEMBL3074984 | 0.87 | HSPA8 (0.72) | HSPA8HSPA5RXFP1SMN1; SMN2LMNA | |
| SCHEMBL6822434 | 0.87 | HSPA8 (0.63) | HSPA8HSPA5RXFP1SMN1; SMN2LMNA | |
| SCHEMBL4376135 | 0.87 | HSPA8 (0.66) | HSPA8HSPA5RXFP1SMN1; SMN2LMNA | |
| SCHEMBL1097926 | 0.85 | HSPA8 (0.75) | HSPA8HSPA5RXFP1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3622092-A2 | METHODS AND COMPOSITIONS OF USE OF CD8+ TUMOR INFILTRATING LYMPHOCYTE SUBTYPES AND GENE SIGNATURES THEREOF | The Broad Institute, Inc. (US) | 2020-03-18 | — | — | EP | disclosed |
| WO-2018209324-A2 | METHODS AND COMPOSITIONS OF USE OF CD8+ TUMOR INFILTRATING LYMPHOCYTE SUBTYPES AND GENE SIGNATURES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2018-11-15 | — | — | WO | disclosed |
| EP-2019834-A1 | ECTONUCLEOTIDASE INHIBITORS | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2009-02-04 | — | — | EP | disclosed |
| WO-2007135195-A1 | ECTONUCLEOTIDASE INHIBITORS | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2007-11-29 | — | — | WO | disclosed |