SCHEMBL4376535

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4370251	0.87	SLC6A4 (0.40)	SMN1; SMN2TDP1SLC6A4SLC6A2OPRM1
	SCHEMBL6784987	0.86	OPRM1 (0.64)	SLC6A4SLC6A2OPRM1OPRK1OPRD1
	SCHEMBL6744715	0.86	OPRM1 (0.64)	SLC6A4SLC6A2OPRM1OPRK1OPRD1
	SCHEMBL6741527	0.86	OPRM1 (0.64)	SLC6A4SLC6A2OPRM1OPRK1OPRD1
	SCHEMBL4374755	0.85	SLC6A4 (0.47)	SLC6A4SLC6A2OPRM1OPRK1OPRD1
	Hydrochloric Acid SCHEMBL6780749	0.85	OPRM1 (0.62)	SLC6A4SLC6A2OPRM1OPRK1OPRD1
	Hydrochloric Acid SCHEMBL6780745	0.85	OPRM1 (0.62)	SLC6A4SLC6A2OPRM1OPRK1OPRD1
	Hydrochloric Acid SCHEMBL7186390	0.85	OPRM1 (0.62)	SLC6A4SLC6A2OPRM1OPRK1OPRD1
	SCHEMBL4370585	0.83	SMN1; SMN2 (0.48)	SMN1; SMN2TDP1SLC6A4SLC6A2OPRM1
	SCHEMBL4374880	0.83	SLC6A2 (0.66)	SLC6A4SLC6A2OPRM1OPRK1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.