SCHEMBL4376598

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7308399	0.84	KDM4E (0.46)	KDM4EGABRPGABRDGABRA1GABRB1
	SCHEMBL109811	0.81	CLCN2 (0.49)	KDM4EGABRPGABRDGABRA1GABRB1
	SCHEMBL2930434	0.81	KDM4E (0.50)	KDM4EGABRPGABRDGABRA1GABRB1
	SCHEMBL11498747	0.80	MAPT (0.49)	MEN1PTGS2AKR1C3KMT2AALDH1A1
	SCHEMBL30374425	0.79	KDM4E (0.48)	KDM4EGABRPGABRDGABRA1GABRB1
	SCHEMBL7924637	0.79	TSHR (0.47)	KDM4ETSHRCLCN2CYP3A4TTR
	SCHEMBL1457096	0.79	KDM4E (0.48)	KDM4EGABRPGABRDGABRA1GABRB1
	SCHEMBL671326	0.79	TSHR (0.52)	KDM4EGABRPGABRDGABRA1GABRB1
	SCHEMBL29443033	0.79	CYP3A4 (0.48)	KDM4ETSHRCYP3A4MEN1KMT2A
	SCHEMBL22905001	0.79	CYP3A4 (0.48)	KDM4ETSHRCYP3A4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.