Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CLCN2 | P51788 | 3/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.43 |
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | FABP2 | P12104 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17612257 | 0.85 | ALDH1A1 (0.40) | TSHRCLCN2MCL1TTRMEN1 | |
| SCHEMBL109811 | 0.84 | CLCN2 (0.49) | TSHRCLCN2MCL1TTRMEN1 | |
| SCHEMBL28873539 | 0.83 | ALOX15 (0.34) | CLCN2MCL1TTRMEN1AKR1B10 | |
| SCHEMBL16019011 | 0.83 | SMN1; SMN2 (0.35) | CLCN2TTRMEN1AKR1B10ABCB11 | |
| SCHEMBL29814908 | 0.83 | CLCN2 (0.47) | TSHRCLCN2MCL1TTRMEN1 | |
| SCHEMBL108571 | 0.83 | TSHR (0.52) | TSHRCLCN2TTRMEN1AKR1B10 | |
| SCHEMBL1834641 | 0.83 | CLCN2 (0.47) | TSHRCLCN2MCL1TTRMEN1 | |
| SCHEMBL10407716 | 0.81 | CLCN2 (0.44) | TSHRCLCN2KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4556197 | 0.81 | KDM4E (0.53) | TSHRCLCN2MCL1TTRMEN1 | |
| SCHEMBL2977547 | 0.81 | TSHR (0.45) | TSHRCLCN2MCL1TTRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112912410-B | Chloroprene-unsaturated nitrile copolymer, chloroprene-unsaturated nitrile copolymer composition, and vulcanized molded article | 电化株式会社 | 2023-09-01 | — | — | CN | disclosed |
| US-9290515-B2 | Cephem derivative having catechol group | SHIONOGI & CO., LTD (JP) | 2016-03-22 | — | — | US | disclosed |
| US-9238657-B2 | Cephalosporin having catechol group | SHIONOGI & CO., LTD. (JP) | 2016-01-19 | — | — | US | disclosed |
| US-9145425-B2 | Cephem compound having catechol group | SHIONOGI & CO., LTD. (JP) | 2015-09-29 | — | — | US | disclosed |
| US-20140256697-A1 | CEPHEM DERIVATIVE HAVING CATECHOL GROUP | SHIONOGI & CO., LTD. (JP) | 2014-09-11 | — | — | US | disclosed |
| US-20130102583-A1 | CEPHEM COMPOUND HAVING CATECHOL GROUP | SHIONOGI & CO., LTD. (JP) | 2013-04-25 | — | — | US | disclosed |
| US-20110190254-A1 | CEPHALOSPORIN HAVING CATECHOL GROUP | SHIONOGI & CO., LTD. (JP) | 2011-08-04 | — | — | US | disclosed |
| WO-2001083420-A2 | METHOD OF MAKING SUBSTITUTED DIHALO AROMATIC ACID CHLORIDES | OCCIDENTAL CHEMICAL CORPORATION (US) | 2001-11-08 | — | — | WO | disclosed |
| US-6225514-B1 | A MIXTURE OF AN AROMATIC HYDROCARBON, ESTER, NITRILE OR HALOGENATED AROMATIC, A HALOGENATING AGENT AND A STABLE ACID,AND CORROSION RESISTANT, HETEROGENEOUS, SOLID ACID CATALYST OF ?DOPED? MIXED OXIDES; BY-PRODUCT INHIBITION | OCCIDENTAL CHEMICAL CORPORATION | 2001-05-01 | — | — | US | disclosed |
| US-6124512-A | HETEROGENEOUS CATALYST. | OCCIDENTAL CHEMICAL CORPORATION (US) | 2000-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190254-A1 | CEPHALOSPORIN HAVING CATECHOL GROUP | NRDC, LUC7L2, NR0B1 | TSHR 2183/4885CLCN2 519/4885MCL1 2785/4885 |
| US-20130102583-A1 | CEPHEM COMPOUND HAVING CATECHOL GROUP | COMT, EZH1, SETD7 | TSHR 4191/4885CLCN2 297/4885MCL1 3298/4885 |
| US-20140256697-A1 | CEPHEM DERIVATIVE HAVING CATECHOL GROUP | COMT, CEP170, SLC6A3 | TSHR 4287/4885CLCN2 356/4885MCL1 2429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.