Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 9/20 | 0.63 |
| ▸ | ACACA | Q13085 | 4/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4376973 | 1.00 | ACACB (0.63) | ACACBACACAMTNR1AGPR35PARP15 | |
| SCHEMBL9235486 | 0.92 | ACACB (0.75) | ACACBACACAMTNR1AMTNR1B | |
| SCHEMBL8109293 | 0.92 | ACACB (0.75) | ACACBACACAMTNR1AMTNR1B | |
| SCHEMBL8116644 | 0.88 | ACACB (0.58) | ACACBACACAMTNR1APARP15PARP10 | |
| SCHEMBL647889 | 0.87 | ACACB (0.57) | ACACBACACAMTNR1AGPR35PARP15 | |
| SCHEMBL649138 | 0.87 | ACACB (0.57) | ACACBACACAMTNR1AGPR35 | |
| SCHEMBL649137 | 0.87 | ACACB (0.57) | ACACBACACAMTNR1AGPR35 | |
| SCHEMBL647888 | 0.87 | ACACB (0.57) | ACACBACACAMTNR1AGPR35PARP15 | |
| SCHEMBL4952795 | 0.87 | ACACB (0.61) | ACACBACACA | |
| SCHEMBL4952800 | 0.87 | ACACB (0.61) | ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537096-B1 | DERIVATIVES OF DIOXANE-2-ALKYL CARBAMATES, PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2008-09-24 | — | — | EP | claimed |
| EP-1840125-B1 | Intermediates for the preparation of dioxane-2-alkyl carbamates | SANOFI AVENTIS (FR) | 2009-06-24 | — | — | EP | disclosed |
| EP-1537096-B1 | DERIVATIVES OF DIOXANE-2-ALKYL CARBAMATES, PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2008-09-24 | — | — | EP | disclosed |
| EP-1840125-A2 | Derivatives of dioxane-2-alkyl carbamates, preparation thereof and application thereof in therapeutics | sanofi-aventis (FR) | 2007-10-03 | — | — | EP | disclosed |
| EP-1537096-A2 | DERIVATIVES OF DIOXANE-2-ALKYL CARBAMATES, PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | Sanofi-Aventis (FR) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004020430-A2 | DERIVATIVES OF DIOXANE-2-ALKYL CARBAMATES, PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2004-03-11 | — | — | WO | disclosed |