Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 11/20 | 0.75 |
| ▸ | ACACA | Q13085 | 5/20 | 0.60 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8109293 | 1.00 | ACACB (0.75) | ACACBACACAMTNR1AMTNR1B | |
| SCHEMBL4376973 | 0.92 | ACACB (0.63) | ACACBACACAMTNR1AMTNR1B | |
| SCHEMBL4376978 | 0.92 | ACACB (0.63) | ACACBACACAMTNR1AMTNR1B | |
| SCHEMBL8120495 | 0.90 | ACACB (0.76) | ACACBACACAMTNR1AMTNR1B | |
| SCHEMBL8116644 | 0.89 | ACACB (0.58) | ACACBACACAMTNR1A | |
| SCHEMBL7779969 | 0.88 | ACACB (0.78) | ACACBACACAMTNR1AMTNR1B | |
| SCHEMBL9236434 | 0.88 | ACACB (0.78) | ACACBACACAMTNR1AMTNR1B | |
| SCHEMBL9239113 | 0.88 | ACACB (0.78) | ACACBACACAMTNR1AMTNR1B | |
| SCHEMBL8118807 | 0.87 | ACACB (0.71) | ACACBACACAMTNR1AMTNR1B | |
| SCHEMBL647889 | 0.87 | ACACB (0.57) | ACACBACACAMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686394-A1 | Use of N-[[5-(naphthales-1-yl)-1,3-dioxan-2-yl]alkyl]acetamide derivatives for the preparation of medicaments for use in the treatment of neurodegenerative disorders | SYNTHELABO (FR) | 1995-12-13 | — | — | EP | disclosed |