Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.45 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.45 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.45 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30990097 | 0.86 | L3MBTL1 (0.49) | NAMPTL3MBTL1HDAC1MAPTTDP1 | |
| SCHEMBL16308104 | 0.82 | GAA (0.48) | NAMPTL3MBTL1HDAC1MAPTTDP1 | |
| SCHEMBL3180689 | 0.81 | L3MBTL1 (0.61) | NAMPTL3MBTL1HDAC1MAPTTDP1 | |
| SCHEMBL4616649 | 0.80 | MAPK14 (0.53) | NAMPTL3MBTL1HDAC1CYP3A4 | |
| SCHEMBL26847061 | 0.79 | AKT1 (0.52) | NAMPTL3MBTL1HDAC1AKT1MAPT | |
| SCHEMBL30608878 | 0.79 | AKT1 (0.52) | NAMPTL3MBTL1HDAC1AKT1MAPT | |
| SCHEMBL11957489 | 0.79 | L3MBTL1 (0.53) | NAMPTL3MBTL1HDAC1MAPTTDP1 | |
| SCHEMBL7652554 | 0.79 | NPC1 (0.58) | NAMPTL3MBTL1HDAC1MAPTGAA | |
| SCHEMBL7836842 | 0.78 | PCSK9 (0.39) | L3MBTL1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL7688482 | 0.78 | ATM (0.49) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |