Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 10/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4377107 | 1.00 | PTGER4 (0.45) | PTGER4PTGER3USP2HCRTR1HCRTR2 | |
| SCHEMBL11565978 | 0.83 | PTGER4 (0.58) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6684187 | 0.83 | PTGER4 (0.58) | PTGER4PTGER3PTGER2 | |
| SCHEMBL4987836 | 0.77 | PTGER4 (0.44) | PTGER4PTGER3USP2PTGER2ALDH1A1 | |
| SCHEMBL4987198 | 0.77 | PTGER4 (0.51) | PTGER4PTGER3USP2PTGER2ALDH1A1 | |
| SCHEMBL5761771 | 0.77 | PTGER4 (0.46) | PTGER4PTGER3HCRTR1HCRTR2PTGER2 | |
| SCHEMBL5757536 | 0.77 | PTGER4 (0.46) | PTGER4PTGER3HCRTR1HCRTR2PTGER2 | |
| SCHEMBL4376664 | 0.76 | PTGER4 (0.53) | PTGER4PTGER3PTGER2 | |
| SCHEMBL4388295 | 0.76 | PTGER4 (0.53) | PTGER4PTGER3PTGER2 | |
| SCHEMBL4376663 | 0.76 | PTGER4 (0.53) | PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817033-B1 | TREATMENT OF INFLAMMATORY BOWEL DISEASE | ALLERGAN INC (US) | 2009-11-18 | — | — | EP | claimed |