Azelaic Acid

Azelaic Acid

SCHEMBL4377214

CCCC[Sn+2]CCCC.O=C([O-])CCCCCCCC(=O)[O-]

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.60
FABP3 P05413 7/20 0.57
CES2 O00748 4/20 0.50
CES1 P23141 4/20 0.50
FFAR3 O14843 2/20 0.48
HDAC3 O15379 2/20 0.48
HDAC1 Q13547 2/20 0.48
HDAC2 Q92769 2/20 0.48
HDAC8 Q9BY41 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sebacic Acid SCHEMBL8648840 1.00 CA1 (0.60) CA1FABP3CES2CES1FFAR3
Tridecanoate SCHEMBL5459906 0.98 FABP3 (0.60) CA1FABP3CES2CES1
Myristic Acid SCHEMBL9245302 0.98 FABP3 (0.60) CA1FABP3CES2CES1
Dodecanoate SCHEMBL29785432 0.98 FABP3 (0.60) CA1FABP3CES2CES1
Stearic Acid SCHEMBL900922 0.98 FABP3 (0.60) CA1FABP3CES2CES1
Heptanoate SCHEMBL8361326 0.98 FABP3 (0.60) CA1FABP3CES2CES1
Palmitic Acid SCHEMBL2452648 0.98 FABP3 (0.60) CA1FABP3CES2CES1
Dodecanoate SCHEMBL35315 0.98 FABP3 (0.60) CA1FABP3CES2CES1
Nonanoate SCHEMBL8365974 0.98 FABP3 (0.60) CA1FABP3CES2CES1
Dodecanoate SCHEMBL4869587 0.98 FABP3 (0.60) CA1FABP3CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090308001-A1 Substrate and the application Wu, Shaobing (US) 2009-12-17 US disclosed
EP-0850987-B1 Improved PVC foam compositions MORTON INT INC (US) 2002-03-27 EP disclosed
US-5786399-A PVC foam compositions MORTON INTERNATIONAL, INC. (US) 1998-07-28 US disclosed
EP-0850987-A1 Improved PVC foam compositions MORTON INTERNATIONAL, INC. (US) 1998-07-01 EP disclosed
US-5726213-A FOAMING VINYL CHLORIDE POLYMER BY HEATING MIXTURE OF POLYMER, BLOWING AGENT, STABILIZER INCLUDING ORGANOTIN MERCAPTIDE OF MERCAPTOALKYL CARBOXYLATE OR SULFIDE THEREOF, OPTIONAL ORGANOTIN SALT MORTON INTERNATIONAL, INC. (US) 1998-03-10 US disclosed
US-3953385-A VINYL CHLORIDE POLYMER, BLOWING AGENT, DIORGANOTIN MERCAPTIDE M&T CHEMICALS INC. (US) 1976-04-27 US disclosed