Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 12/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13890548 | 0.84 | AR (0.53) | ARKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL17623897 | 0.84 | AR (0.53) | ARCYP1A2CYP2C19HPGDALDH1A1 | |
| SCHEMBL523438 | 0.84 | CYP19A1 (0.54) | ARCYP1A2CYP2C19CYP3A4SLC22A12 | |
| SCHEMBL11752736 | 0.81 | AR (0.57) | ARSLC22A12HPGDKDM4EMEN1 | |
| SCHEMBL4171343 | 0.79 | AR (0.59) | ARCYP1A2CYP2C19CYP3A4SLC22A12 | |
| SCHEMBL304892 | 0.79 | TSHR (0.48) | ARSLC22A12HPGDKDM4EMEN1 | |
| SCHEMBL25865448 | 0.79 | AR (0.48) | AR | |
| SCHEMBL13890508 | 0.78 | AR (0.66) | ARSLC22A12 | |
| SCHEMBL19175514 | 0.77 | HTR2A (0.53) | CYP1A2CYP2C19CYP3A4HPGDMEN1 | |
| SCHEMBL21332929 | 0.77 | AR (0.75) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |