SCHEMBL25865448

SCHEMBL25865448

Cc1cc(Oc2ccc(CO)cc2)ccc1C#N

nearest known ligand 0.70

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
AR P10275 12/20 0.48
LTA4H P09960 1/20 0.47
MRGPRX4 Q96LA9 1/20 0.46
MAOB P27338 1/20 0.38
NR1H2 P55055 1/20 0.37
NR1H3 Q13133 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3568078 0.85 LTA4H (0.52) ARLTA4HMAOB
SCHEMBL14670168 0.82 AR (0.55) ARMRGPRX4
SCHEMBL536160 0.81 TSHR (0.43) ARMRGPRX4
SCHEMBL17623897 0.80 AR (0.53) ARLTA4HMRGPRX4
SCHEMBL13890548 0.80 AR (0.53) AR
SCHEMBL4377219 0.79 AR (0.53) AR
SCHEMBL9889475 0.76 AR (0.52) AR
SCHEMBL9889478 0.76 AR (0.55) AR
SCHEMBL14667748 0.76 LTA4H (0.52) LTA4HNR1H2NR1H3
SCHEMBL9889466 0.76 LTA4H (0.52) LTA4HMRGPRX4NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4212537-A1 LIQUID PROCESSIBLE DIPHTHALONITRILE MONOMERS AND RESINS Rolls-Royce plc (GB) 2023-07-19 EP disclosed