SCHEMBL4377289

SCHEMBL4377289

CC(=O)OC1CC2(C(F)F)C=CC1O2

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4383048 0.70 CHRM2 (0.32) CHRM2CHRM4CHRM1CHRM3
SCHEMBL3907947 0.58 TSHR (0.33) CHRM2CHRM4CHRM1CHRM3
SCHEMBL29182417 0.57 KMT2A (0.33) CHRM2CHRM1
SCHEMBL1088537 0.56 TSHR (0.37) CHRM2CHRM4CHRM1CHRM3
SCHEMBL27656244 0.55
SCHEMBL14354717 0.55 CHRM2 (0.42) CHRM2CHRM4CHRM1CHRM3
SCHEMBL10440862 0.55 CHRM2 (0.42) CHRM2CHRM4CHRM1CHRM3
SCHEMBL9073688 0.54
SCHEMBL2813758 0.54 TSHR (0.35)
SCHEMBL9812742 0.54

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8211984-B2 Ring-opening metathesis polymer, hydrogenated product thereof, method for preparing the same, and use thereof MITSUI CHEMICALS, INC. (JP) 2012-07-03 US disclosed
US-20090215974-A1 RING-OPENING METATHESIS POLYMER, HYDROGENATED PRODUCT THEREOF, METHOD FOR PREPARING THE SAME, AND USE THEREOF MITSUI CHEMICALS INC (JP) 2009-08-27 US disclosed
EP-2045280-A1 RING-OPENING METATHESIS POLYMERS, PRODUCTS OF HYDROGENATION THEREOF, PROCESS FOR PRODUCTION OF THE SAME AND USES THEREOF Mitsui Chemicals, Inc. (JP) 2009-04-08 EP disclosed