Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL514650 | 1.00 | MAPT (0.64) | MAPTABCC4ALDH1A1LMNAPAOX | |
| SCHEMBL3123064 | 1.00 | MAPT (0.64) | MAPTABCC4ALDH1A1LMNAPAOX | |
| SCHEMBL3112070 | 1.00 | MAPT (0.64) | MAPTABCC4ALDH1A1LMNAPAOX | |
| SCHEMBL19861007 | 1.00 | MAPT (0.64) | MAPTABCC4ALDH1A1LMNAPAOX | |
| SCHEMBL15753807 | 1.00 | MAPT (0.64) | MAPTABCC4ALDH1A1LMNAPAOX | |
| SCHEMBL515223 | 1.00 | MAPT (0.64) | MAPTABCC4ALDH1A1LMNAPAOX | |
| SCHEMBL4370853 | 1.00 | MAPT (0.64) | MAPTABCC4ALDH1A1LMNAPAOX | |
| Ethylene SCHEMBL11462976 | 0.98 | MAPT (0.61) | MAPTABCC4ALDH1A1LMNAPAOX | |
| SCHEMBL514535 | 0.98 | — | — | |
| SCHEMBL27686771 | 0.92 | TSHR (0.64) | MAPTABCC4ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444142-B1 | POLYQUINOLINE COPOLYMERS | HITACHI CHEMICAL CO LTD (JP) | 2000-03-29 | — | — | EP | claimed |
| US-20110256161-A1 | METHODS FOR ENHANCING IMMUNE RESPONSE | AMINEX THERAPEUTICS INC. (US) | 2011-10-20 | — | — | US | disclosed |
| US-20090117478-A1 | Polycarbonate Resin and Electrophotographic Photosensitive Body Using Same | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2009-05-07 | — | — | US | disclosed |