Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL514650 | 1.00 | MAPT (0.64) | MAPTABCC4ALDH1A1LMNAPAOX | |
| SCHEMBL3123064 | 1.00 | MAPT (0.64) | MAPTABCC4ALDH1A1LMNAPAOX | |
| SCHEMBL4377338 | 1.00 | MAPT (0.64) | MAPTABCC4ALDH1A1LMNAPAOX | |
| SCHEMBL3112070 | 1.00 | MAPT (0.64) | MAPTABCC4ALDH1A1LMNAPAOX | |
| SCHEMBL15753807 | 1.00 | MAPT (0.64) | MAPTABCC4ALDH1A1LMNAPAOX | |
| SCHEMBL515223 | 1.00 | MAPT (0.64) | MAPTABCC4ALDH1A1LMNAPAOX | |
| SCHEMBL4370853 | 1.00 | MAPT (0.64) | MAPTABCC4ALDH1A1LMNAPAOX | |
| Ethylene SCHEMBL11462976 | 0.98 | MAPT (0.61) | MAPTABCC4ALDH1A1LMNAPAOX | |
| SCHEMBL514535 | 0.98 | — | — | |
| SCHEMBL27686771 | 0.92 | TSHR (0.64) | MAPTABCC4ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11732244-B2 | Methods for increasing the infectivity of viruses utilizing alkyne-modified fatty acids | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-08-22 | — | — | US | disclosed |
| US-20200407698-A1 | METHODS FOR INCREASING THE INFECTIVITY OF VIRUSES | Life Technologies Corporation | 2020-12-31 | — | — | US | disclosed |
| US-9890361-B2 | Methods for increasing the infectivity of viruses utilizing alkyne-modified fatty acids | Life Technologies Corporation (US) | 2018-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11732244-B2 | Methods for increasing the infectivity of viruses utilizing alkyne-modified fatty acids | LIPA, NPC1L1, LIPC | MAPT 2713/4885ABCC4 3247/4885ALDH1A1 2258/4885 |
| US-20200407698-A1 | METHODS FOR INCREASING THE INFECTIVITY OF VIRUSES | LIPA, NPC1L1, LIPC | MAPT 2589/4885ABCC4 3157/4885ALDH1A1 2781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.