Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 3/20 | 0.38 |
| ▸ | CTSK | P43235 | 3/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2454946 | 0.83 | MEN1 (0.54) | MAOAMAOBMEN1GAAKMT2A | |
| SCHEMBL570983 | 0.83 | MEN1 (0.54) | MAOAMAOBMEN1GAAKMT2A | |
| SCHEMBL19672407 | 0.83 | MEN1 (0.46) | MAOAMAOBMEN1GAAKMT2A | |
| SCHEMBL1186668 | 0.83 | MEN1 (0.54) | MAOAMAOBMEN1GAAKMT2A | |
| SCHEMBL14015716 | 0.81 | MEN1 (0.45) | MAOAMAOBMEN1GAAKMT2A | |
| SCHEMBL7403514 | 0.81 | MEN1 (0.45) | MAOAMAOBMEN1GAAKMT2A | |
| SCHEMBL9733251 | 0.81 | MAOA (0.45) | MAOAMAOBMEN1GAAKMT2A | |
| SCHEMBL14155384 | 0.81 | MEN1 (0.45) | MAOAMAOBMEN1GAAKMT2A | |
| SCHEMBL18515428 | 0.81 | MAOA (0.45) | MAOAMAOBMEN1GAAKMT2A | |
| SCHEMBL5478424 | 0.81 | MAOA (0.45) | MAOAMAOBMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3009425-B1 | ALPHA-OXOACYLAMINOCAPROLACTAM | SEIKAGAKU KOGYO CO LTD (JP) | 2018-06-06 | — | — | EP | disclosed |
| EP-3009444-B1 | ALPHA-OXOACYL AMINO-CAPROLACTAM DERIVATIVE | SEIKAGAKU KOGYO CO LTD (JP) | 2017-12-20 | — | — | EP | disclosed |
| EP-1773868-B1 | SUBSTITUTED PROLINES AS INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE | SCHERING CORP (US) | 2009-07-15 | — | — | EP | disclosed |
| EP-2038272-A2 | PYRIDINONYL PDK1 INHIBITORS | Sunesis Pharmaceuticals, Inc. (US) | 2009-03-25 | — | — | EP | disclosed |
| WO-2008005457-A2 | PYRIDINONYL PDK1 INHIBITORS | SUNESIS PHARMACEUTICALS (US) | 2008-01-10 | — | — | WO | disclosed |