Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 13/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 8/20 | 0.42 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.39 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4396093 | 0.89 | HSP90AA1 (0.58) | HSP90AA1MAPK14HSP90AB1HSP90B1TRAP1 | |
| SCHEMBL28934605 | 0.89 | HSP90AA1 (0.45) | HSP90AA1MAPK14HSP90AB1 | |
| SCHEMBL28704117 | 0.88 | HSP90AA1 (0.48) | HSP90AA1MAPK14HSP90AB1HSP90B1TRAP1 | |
| SCHEMBL28701259 | 0.88 | HSP90AA1 (0.44) | HSP90AA1MAPK14HSP90AB1 | |
| SCHEMBL28710751 | 0.88 | MAPK14 (0.46) | HSP90AA1MAPK14HSP90AB1 | |
| SCHEMBL4392433 | 0.87 | HSP90AA1 (0.47) | HSP90AA1MAPK14HSP90AB1HSP90B1TRAP1 | |
| SCHEMBL4062363 | 0.87 | MAPK14 (0.48) | HSP90AA1MAPK14HSP90AB1 | |
| SCHEMBL28702727 | 0.87 | MAPK14 (0.46) | HSP90AA1MAPK14HSP90AB1 | |
| SCHEMBL28690426 | 0.87 | HSP90AA1 (0.44) | HSP90AA1MAPK14HSP90AB1HSP90B1TRAP1 | |
| SCHEMBL28704100 | 0.86 | HSP90AA1 (0.48) | HSP90AA1MAPK14HSP90AB1HSP90B1TRAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |