Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 14/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 11/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13848422 | 0.88 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1MAPK14LMNATP53 | |
| SCHEMBL28701252 | 0.88 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1MAPK14MAPK13MAPK12 | |
| SCHEMBL4377799 | 0.86 | HSP90AA1 (0.58) | HSP90AA1HSP90AB1MAPK14HSP90B1TRAP1 | |
| SCHEMBL4071241 | 0.86 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1LMNATP53CYP1A2 | |
| SCHEMBL4068772 | 0.85 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1MAPK14LMNATP53 | |
| SCHEMBL4396093 | 0.84 | HSP90AA1 (0.58) | HSP90AA1HSP90AB1MAPK14HSP90B1TRAP1 | |
| SCHEMBL28701272 | 0.83 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1GABRA1GABRB2HSP90B1 | |
| SCHEMBL4392433 | 0.82 | HSP90AA1 (0.47) | HSP90AA1HSP90AB1MAPK14HSP90B1TRAP1 | |
| SCHEMBL28934605 | 0.81 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1MAPK14 | |
| SCHEMBL28704117 | 0.81 | HSP90AA1 (0.48) | HSP90AA1HSP90AB1MAPK14HSP90B1TRAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114014849-A | 4, 5-diaryl oxazole compound and application thereof | 福建医科大学 | 2022-02-08 | — | — | CN | disclosed |