Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.85 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.85 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.85 |
| ▸ | TSHR | P16473 | 4/20 | 0.85 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.85 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.73 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.65 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenanthrene SCHEMBL201780 | 0.96 | ALDH1A1 (0.92) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| Phenanthrene SCHEMBL28634294 | 0.93 | HSD17B10 (0.86) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| Phenanthrene SCHEMBL2321409 | 0.93 | ALDH1A1 (0.86) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| Phenanthrene SCHEMBL29477074 | 0.92 | CYP2A6 (1.00) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| Phenanthrene SCHEMBL29358486 | 0.92 | CYP2A6 (1.00) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| Phenanthrene SCHEMBL27458043 | 0.92 | CYP2A6 (1.00) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| Phenanthrene SCHEMBL8873977 | 0.92 | CYP2A6 (1.00) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| Phenanthrene SCHEMBL7643 | 0.92 | CYP2A6 (1.00) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| Phenanthrene SCHEMBL30932938 | 0.92 | CYP2A6 (1.00) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| Phenanthrene SCHEMBL1330750 | 0.92 | CYP2A6 (1.00) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090299093-A1 | Preparation of Gamma-Amino Acids Having Affinity for The Alpha-2-Delta Protein | PFIZER INC. | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090299093-A1 | Preparation of Gamma-Amino Acids Having Affinity for The Alpha-2-Delta Protein | SCN2A, CACNG2, SCN1A | ALDH1A1 2226/4885CYP2A6 3609/4885HSD17B10 4039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.