SCHEMBL4377967

SCHEMBL4377967

CCC(C(=O)O)C(C)(C)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.46
HIF1A Q16665 1/20 0.46
KIF11 P52732 9/20 0.44
MAPT P10636 1/20 0.42
KMT2A Q03164 1/20 0.42
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
HDAC9 Q9UKV0 1/20 0.40
HDAC5 Q9UQL6 1/20 0.40
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
MME P08473 1/20 0.38
ACE P12821 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1829558 0.85 MAPT (0.48) CYP2C19HIF1AKIF11MAPTKMT2A
SCHEMBL9755832 0.83 CYP2C19 (0.48) CYP2C19HIF1AKIF11MAPTKMT2A
SCHEMBL1028846 0.82 KMT2A (0.44) CYP2C19HIF1AKIF11MAPTKMT2A
SCHEMBL9971684 0.81 CYP2C19 (0.43) CYP2C19HIF1AKIF11MAPTKMT2A
SCHEMBL4378855 0.81 CYP1A2 (0.50) CYP2C19HIF1AMAPTKMT2ACYP1A2
SCHEMBL4375323 0.79 CYP2C19 (0.49) CYP2C19HIF1AKIF11MAPTKMT2A
SCHEMBL28779828 0.78 KIF11 (0.43) CYP2C19HIF1AKIF11KMT2ACYP1A2
SCHEMBL8909445 0.78 CYP2C19 (0.40) CYP2C19HIF1AKIF11MAPTKMT2A
SCHEMBL8909447 0.78 CYP2C19 (0.40) CYP2C19HIF1AKIF11MAPTKMT2A
SCHEMBL8854204 0.75 MAPT (0.48) CYP2C19HIF1AKIF11MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116940466-A Consumer products 联合利华知识产权控股有限公司 2023-10-24 CN disclosed
CN-109311789-B Process for preparing 2, 3-unsaturated alcohols 巴斯夫欧洲公司 2023-04-04 CN disclosed
CN-112469807-B Benefit agent delivery particles 联合利华知识产权控股有限公司 2022-07-26 CN disclosed
CN-109310974-B Process for preparing microcapsules 西姆莱斯股份公司 2022-07-19 CN disclosed
CN-111770982-B Laundry detergent 联合利华知识产权控股有限公司 2022-05-27 CN disclosed
CN-113544250-A Composition comprising a metal oxide and a metal oxide 联合利华知识产权控股有限公司 2021-10-22 CN disclosed
CN-111615551-B Laundry detergent 联合利华知识产权控股有限公司 2021-10-01 CN disclosed
CN-113242750-A Microcapsules 西姆莱斯股份公司 2021-08-10 CN disclosed
CN-108367088-B Composition and delivery system and filling for spraying two or more compositions 约翰逊父子公司 2021-07-06 CN disclosed
CN-108473484-B Compounds useful as TRPM8 modulators 弗门尼舍公司 2021-06-29 CN disclosed
CN-111770982-A Laundry detergent 荷兰联合利华有限公司 2020-10-13 CN disclosed
CN-111615551-A Laundry detergent 荷兰联合利华有限公司 2020-09-01 CN disclosed
CN-107072900-B High coverage, low odor malodor counteracting compounds and methods of use 国际香料和香精公司 2020-03-20 CN disclosed
CN-105722495-B Polyurea or polyurethane capsules 国际香料和香精公司 2020-02-28 CN disclosed
CN-102753522-B Substituted pyrrolidine-2-carboxamides HOFFMANN LA ROCHE 2013-11-27 CN disclosed
US-7626023-B2 Compounds for treating tumors WYETH (US) 2009-12-01 US disclosed
US-20080221181-A1 COMPOUNDS FOR TREATING TUMORS WYETH HOLDINGS CORPORATION (US) 2008-09-11 US disclosed
US-7390910-B2 Compounds for treating tumors WYETH (US) 2008-06-24 US disclosed
WO-2005016958-A2 COMPOUNDS FOR TREATING TUMORS WYETH HOLDINGS CORPORATION (US) 2005-02-24 WO disclosed
US-20050037977-A1 Compounds for treating tumors WYETH HOLDINGS CORPORATION (US) 2005-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080221181-A1 COMPOUNDS FOR TREATING TUMORS RB1, MRPL9, BCOR CYP2C19 2819/4885HIF1A 1664/4885KIF11 1677/4885
US-20050037977-A1 Compounds for treating tumors RB1, MRPL9, BCOR CYP2C19 2819/4885HIF1A 1664/4885KIF11 1677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.