Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6702832 | 0.89 | ABCB1 (0.36) | L3MBTL1GAAPOLBMAPTNPSR1 | |
| SCHEMBL6702825 | 0.89 | ABCB1 (0.36) | L3MBTL1GAAPOLBMAPTNPSR1 | |
| SCHEMBL6761592 | 0.88 | MCL1 (0.43) | CNR1L3MBTL1GAAMCL1CALCRL | |
| SCHEMBL6761593 | 0.88 | MCL1 (0.43) | CNR1L3MBTL1GAAMCL1CALCRL | |
| SCHEMBL6761596 | 0.88 | MCL1 (0.43) | CNR1L3MBTL1GAAMCL1CALCRL | |
| SCHEMBL6761598 | 0.88 | MCL1 (0.43) | CNR1L3MBTL1GAAMCL1CALCRL | |
| SCHEMBL6702531 | 0.86 | L3MBTL1 (0.33) | L3MBTL1GAAPOLBMAPTNPSR1 | |
| SCHEMBL6702534 | 0.86 | L3MBTL1 (0.33) | L3MBTL1GAAPOLBMAPTNPSR1 | |
| SCHEMBL4377560 | 0.80 | GAA (0.42) | L3MBTL1GAAKMT2AMCL1CALCRL | |
| SCHEMBL4377559 | 0.80 | GAA (0.42) | L3MBTL1GAAKMT2AMCL1CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903353-B1 | Imidazolidine derivates, their preparation and use, and pharmaceutical compositions containing them | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-11-25 | — | — | EP | disclosed |
| EP-0903353-A1 | Imidazolidine derivates, their preparation and use, and pharmaceutical compositions containing them | Hoechst Marion Roussel Deutschland GmbH (DE) | 1999-03-24 | — | — | EP | disclosed |