Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.59 |
| ▸ | ITGAV | P06756 | 20/20 | 0.59 |
| ▸ | ITGB6 | P18564 | 15/20 | 0.59 |
| ▸ | ITGB5 | P18084 | 8/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2837544 | 0.88 | ITGB3 (0.73) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL4063045 | 0.87 | ITGB3 (0.63) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL2838930 | 0.81 | ITGB3 (0.78) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL6178863 | 0.79 | ITGB3 (0.75) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL2841497 | 0.77 | ITGAV (0.74) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL29207458 | 0.76 | ITGB3 (0.62) | ITGB3ITGAVITGB5 | |
| SCHEMBL15673930 | 0.76 | ITGB3 (0.78) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL2839364 | 0.74 | ITGB3 (0.78) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL2835442 | 0.74 | ITGB3 (1.00) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL2838713 | 0.74 | ITGB3 (0.84) | ITGB3ITGAVITGB6ITGB5ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009061448-A9 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PROTEINURIC DISEASES | THE GENERAL HOSPITAL CORPORATION (US) | 2009-08-13 | — | — | WO | disclosed |