⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4378046 | 0.84 | — | — | |
| SCHEMBL13034028 | 0.79 | — | — | |
| SCHEMBL13138904 | 0.78 | — | — | |
| SCHEMBL13138905 | 0.78 | — | — | |
| SCHEMBL118394 | 0.76 | DPP4 (0.37) | — | |
| SCHEMBL12435676 | 0.74 | — | — | |
| SCHEMBL223841 | 0.73 | SLC6A3 (0.33) | — | |
| SCHEMBL22601667 | 0.73 | — | — | |
| SCHEMBL441447 | 0.72 | — | — | |
| SCHEMBL15925124 | 0.71 | PPARG (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760811-B1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 MODULATORS | INST NAT SANTE RECH MED (FR) | 2009-11-18 | — | — | EP | disclosed |
| WO-1996029315-A2 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-09-26 | — | — | WO | disclosed |