Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 12/20 | 0.41 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21578111 | 0.92 | MAPT (0.56) | MAPTLMNAKDM4ECYP1A2CYP3A4 | |
| SCHEMBL21578127 | 0.82 | MAPT (0.46) | MAPTLMNAKDM4ECYP1A2CYP3A4 | |
| SCHEMBL4302102 | 0.78 | MAPT (0.71) | MAPTLMNAKDM4ECYP1A2CYP3A4 | |
| SCHEMBL21677421 | 0.75 | KDM4E (0.42) | MAPTLMNAKDM4ECYP1A2CYP3A4 | |
| SCHEMBL20740893 | 0.75 | KDM4E (0.42) | MAPTLMNAKDM4ECYP1A2CYP3A4 | |
| SCHEMBL2649168 | 0.74 | LMNA (0.58) | MAPTLMNAKDM4ECYP1A2CYP3A4 | |
| SCHEMBL13907344 | 0.73 | MAPT (0.73) | MAPTLMNAKDM4ECYP1A2CYP3A4 | |
| SCHEMBL4159679 | 0.72 | TTR (0.32) | — | |
| SCHEMBL9728 | 0.71 | MAPT (1.00) | MAPTLMNAKDM4ECYP1A2CYP3A4 | |
| SCHEMBL7713106 | 0.71 | LMNA (0.48) | MAPTLMNACYP1A2CYP3A4NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009068885-A1 | DINUCLEAR, QUADRUPLY-STRANDED COMPOUNDS COMPRISING PALLADIUM OR PLATINUM | THE UNIVERSITY OF BIRMINGHAM (GB) | 2009-06-04 | — | — | WO | disclosed |