Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4385480 | 1.00 | SLC6A3 (1.00) | SLC6A3SLC6A4 | |
| SCHEMBL4384336 | 0.87 | SLC6A3 (1.00) | SLC6A3SLC6A4 | |
| SCHEMBL4376470 | 0.87 | SLC6A3 (1.00) | SLC6A3SLC6A4 | |
| SCHEMBL4384718 | 0.87 | SLC6A3 (1.00) | SLC6A3SLC6A4 | |
| SCHEMBL4387522 | 0.87 | SLC6A3 (1.00) | SLC6A3SLC6A4 | |
| SCHEMBL6765772 | 0.87 | SLC6A3 (1.00) | SLC6A3SLC6A4 | |
| SCHEMBL4384767 | 0.87 | SLC6A3 (1.00) | SLC6A3SLC6A4 | |
| SCHEMBL6767667 | 0.86 | SLC6A3 (0.76) | SLC6A3SLC6A4 | |
| SCHEMBL6772576 | 0.86 | SLC6A3 (0.75) | SLC6A3SLC6A4 | |
| SCHEMBL6762816 | 0.84 | SLC6A3 (0.72) | SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1493744-B1 | Tropane analogs and methods for inhibition of monoamine transport | ORGANIX INC (US) | 2009-11-25 | — | — | EP | claimed |
| EP-1493744-A1 | Tropane analogs and methods for inhibition of monoamine transport | ORGANIX, INC. (US) | 2005-01-05 | — | — | EP | claimed |
| US-20030069269-A1 | Tropane analogs and methods for inhibition of monoamine | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-04-10 | — | — | US | claimed |
| US-6417221-B1 | SEROTONIN REUPTAKE INHIBITORS OR ANTISEROTONIN AGENTS | ORGANIX, INC. | 2002-07-09 | — | — | US | claimed |
| US-20020010207-A1 | Tropane analogs and methods for inhibition of monoamine transport | WILMINGTON TRUST (LONDON) LIMITED, AS SECURITY AGENT (GB) | 2002-01-24 | — | — | US | claimed |
| EP-1493744-B1 | Tropane analogs and methods for inhibition of monoamine transport | ORGANIX INC (US) | 2009-11-25 | — | — | EP | disclosed |
| US-6677338-B2 | FOR THERAPY OF DEPRESSION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2004-01-13 | — | — | US | disclosed |
| US-6670375-B2 | Particularly, 8-aza-, 8-carbo- and 8-oxo- tropanes having 6-or 7-substituents; preferred are the dopamine transporter, the serotonin transporter and the norepinephrine transporter. | ORGANIX, INC. | 2003-12-30 | — | — | US | disclosed |
| US-20030105096-A1 | Serotonin transport inhibitors | WILMINGTON TRUST (LONDON) LIMITED, AS SECURITY AGENT (GB) | 2003-06-05 | — | — | US | disclosed |
| US-20030069269-A1 | Tropane analogs and methods for inhibition of monoamine | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-04-10 | — | — | US | disclosed |
| US-6417221-B1 | SEROTONIN REUPTAKE INHIBITORS OR ANTISEROTONIN AGENTS | ORGANIX, INC. | 2002-07-09 | — | — | US | disclosed |
| US-6353105-B1 | INHIBITORS OF 5-HYDROXY-TRYPTAMINE REUPTAKE OF A MONOAMINE TRANSPORTER; ANALOGS OF COCAINE; | ORGANIX, INC. | 2002-03-05 | — | — | US | disclosed |
| US-20020010207-A1 | Tropane analogs and methods for inhibition of monoamine transport | WILMINGTON TRUST (LONDON) LIMITED, AS SECURITY AGENT (GB) | 2002-01-24 | — | — | US | disclosed |
| US-5948933-A | THERAPY FOR DRUG ABRUSE | ORGANIX, INC. (US) | 1999-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069269-A1 | Tropane analogs and methods for inhibition of monoamine | SLC6A2, SLC6A4, SLC18A2 | SLC6A3 4/4885SLC6A4 2/4885 |
| US-20030105096-A1 | Serotonin transport inhibitors | SLC6A4, SLC6A2, SLC18A2 | SLC6A3 4/4885SLC6A4 1/4885 |
| US-20020010207-A1 | Tropane analogs and methods for inhibition of monoamine transport | SLC6A2, SLC6A4, SLC6A3 | SLC6A3 3/4885SLC6A4 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.