Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.37 |
| ▸ | ESR1 | P03372 | 4/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4379354 | 1.00 | KMT2A (0.39) | KMT2APRSS1ESR1SMPD1 | |
| Trifluoroacetic Acid SCHEMBL4392043 | 0.91 | KMT2A (0.40) | KMT2AESR1SMPD1 | |
| Trifluoroacetic Acid SCHEMBL4392038 | 0.91 | KMT2A (0.40) | KMT2AESR1SMPD1 | |
| SCHEMBL4383633 | 0.85 | KMT2A (0.45) | KMT2AESR1SMPD1 | |
| SCHEMBL4379687 | 0.82 | KMT2A (0.50) | KMT2A | |
| SCHEMBL4543078 | 0.80 | PRSS1 (0.38) | KMT2APRSS1SMPD1 | |
| SCHEMBL4543075 | 0.80 | PRSS1 (0.38) | KMT2APRSS1SMPD1 | |
| SCHEMBL4379265 | 0.79 | KMT2A (0.46) | KMT2AESR1SMPD1 | |
| SCHEMBL4543312 | 0.79 | KMT2A (0.49) | KMT2ASMPD1 | |
| SCHEMBL8794353 | 0.78 | MAOB (0.47) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | claimed |
| EP-0760811-B1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 MODULATORS | INST NAT SANTE RECH MED (FR) | 2009-11-18 | — | — | EP | disclosed |
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | disclosed |
| EP-0760811-A1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H 3? (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-03-12 | — | — | EP | disclosed |
| WO-1996029315-A2 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-09-26 | — | — | WO | disclosed |